Characterization of a novel HLA-C allele, HLA-C*05:278N

Magali Devriese^{1

2}, Sephora Da Silva¹, Maryvonnick Carmagnat¹, Jean-Luc Taupin^{1

2}

Affiliations

¹ Laboratoire d'Immunologie et Histocompatibilité, Hôpital Saint Louis, Paris, France.
² INSERM UMR976, Institut de Recherche Saint-Louis, Université de Paris, Paris, France.

Magali Devriese et al. HLA. 2023 Sep.

. 2023 Sep;102(3):369-370.

doi: 10.1111/tan.15117. Epub 2023 May 24.

Magali Devriese^{1

2}, Sephora Da Silva¹, Maryvonnick Carmagnat¹, Jean-Luc Taupin^{1

2}

¹ Laboratoire d'Immunologie et Histocompatibilité, Hôpital Saint Louis, Paris, France.
² INSERM UMR976, Institut de Recherche Saint-Louis, Université de Paris, Paris, France.

Abstract

The novel HLA-C*05:278N allele has a premature stop codon in exon 4.

Keywords: HLA-C; nanotype sequencing; null allele; sequencing-based typing.

1. Mosbruger TL, Dinou A, Duke JL, et al. Utilizing nanopore sequencing technology for the rapid and comprehensive characterization of eleven HLA loci; addressing the need for deceased donor expedited HLA typing. Hum Immunol. 2020;81(8):413-422. doi:10.1016/j.humimm.2020.06.004
1. Barker DJ, Maccari G, Georgiou X, et al. The IPD-IMGT/HLA Database. Nucleic Acids Res. 2023;51(D1):D1053-D1060. doi:10.1093/nar/gkac1011
1. Marsh SGE, Albert ED, Bodmer WF, et al. Nomenclature for factors of the HLA system, 2010. Tissue Antigens. 2010;75(4):291-455. doi:10.1111/j.1399-0039.2010.01466.x