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. 2023 Jul 12;40(4):298-299.
doi: 10.4274/balkanmedj.galenos.2023.2023-3-60. Epub 2023 May 25.

Germinoma Misdiagnosed as Lymphocytic Hypophysitis

Serdar Şahin  1 , Ozan Başkurt  2 , Nil Çomunoğlu  3 , Pınar Kadıoğlu  1 , Nurperi Gazioğlu  2
Affiliations

Germinoma Misdiagnosed as Lymphocytic Hypophysitis

Serdar Şahin et al. Balkan Med J. .
No abstract available

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Conflict of interest statement

Conflict of Interest: No conflict of interest was declared by the authors.

Figures

Figure 1
Figure 1
a) Pituitary magnetic resonance imaging (T1-weighted, coronal); thickening on the upper half of the pituitary stalk extending to the right half of the chiasm, b) Yellowish soft mass in the upper part of the pituitary stalk, c) Larger tumor cells (black arrow) with atypical nuclei and small reactive lymphoid cells (yellow arrow) (hematoxylin and eosin staining *400), d) SALL4(+) large atypical tumor cells (SALL4 *400).
See this image and copyright information in PMC

References

    1. Packer RJ, Cohen BH, Cooney K. Intracranial germ cell tumors. Oncologist. 2000;5:312–20. - PubMed
    1. Prete A, Salvatori R. Hypophysitis. In: Feingold KR, Anawalt B, Blackman MR, et al. editors. South Dartmouth (MA) 2000.
    1. Dias D, Vilar H, Passos J, Leite V. Central diabetes insipidus caused by a pituitary stalk germinoma resembling infundibuloneurohypophysitis. BMJ Case Rep. 2020;13 - PMC - PubMed
    1. Pal R, Rai A, Vaiphei K, et al. Intracranial Germinoma Masquerading as Secondary Granulomatous Hypophysitis: A Case Report and Review of Literature. Neuroendocrinology. 2020;110:422–9. - PubMed
    1. Miettinen M, Wang Z, McCue PA, et al. SALL4 expression in germ cell and non-germ cell tumors: a systematic immunohistochemical study of 3215 cases. Am J Surg Pathol. 2014;38:410–20. - PMC - PubMed

Supplementary concepts

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