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. 2023 Jun 20;12(6):e0018223.
doi: 10.1128/mra.00182-23. Epub 2023 May 25.

Hepatitis B Virus Genotype E/A Recombinants from Blood Donors in Beira, Mozambique

Barbara Tyler  1 , Heidi L Meeds  1 , Elizabeth A Odegard  1 , Nalia Ismael  2 , Adolfo Vubil  2 , Ana Flora Zicai  2 , Nédio Mabunda  2 , Jason T Blackard  1
Affiliations

Hepatitis B Virus Genotype E/A Recombinants from Blood Donors in Beira, Mozambique

Barbara Tyler et al. Microbiol Resour Announc. .

Abstract

Hepatitis B virus (HBV) is endemic in many parts of sub-Saharan Africa. Here, we present 5 full-length HBV recombinant genomes from blood donors in Beira, Mozambique. The genomes are recombinants between genotypes E and A and are distantly related to one another, based on their genetic distances.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

FIG 1
FIG 1
(A) Phylogenetic tree of full-length recombinant sequences from Mozambique. Each sequence is labeled with its GenBank accession number, country of origin, and genotype. Full-length recombinant sequences from Mozambique are colored in red. (B) Recombination prediction profiles. Profiles were evaluated using the jpHMM program, which employs a probabilistic approach to compare a nucleic acid or protein sequence S to a given multiple alignment A of a sequence family for which a classification into subtypes is available. jpHMM does not align and compare a database sequence S to the multiple alignment A as a whole; rather, it aligns local segments of S to those segments of individual sequences from A that are most similar to them. Recombination analysis of circular genomes is performed with artificially linearized sequences of the circular genomes using linear models. Samples are identified by their patient identification number.
See this image and copyright information in PMC

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