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. 2023 May 9;9(3):00020-2023.
doi: 10.1183/23120541.00020-2023. eCollection 2023 May.

Persistence of a SARS-CoV-2 T-cell response in patients with long COVID and lung sequelae after COVID-19

Tamara Cruz  1   2   3 , Núria Mendoza  1   3 , Gema M Lledó  4   3 , Lídia Perea  1   2 , Núria Albacar  1   2   5 , Alvar Agustí  1   2   5 , Jacobo Sellares  1   2   5 , Oriol Sibila  1   2   5   6 , Rosa Faner  1   2   7   6
Affiliations

Persistence of a SARS-CoV-2 T-cell response in patients with long COVID and lung sequelae after COVID-19

Tamara Cruz et al. ERJ Open Res. .

Abstract

1 year after an acute COVID-19 episode, patients with either lung sequelae or long COVID show a stronger SARS-CoV-2-specific T-cell response than fully recovered individuals, suggesting persistent cell stimulation by residual viral reservoirs https://bit.ly/40bPZm7.

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Conflict of interest statement

Conflict of interest: T. Cruz reports support for the present manuscript from AGAUR (PANDEMIES 2020). Conflict of interest: N. Mendoza reports support for the present manuscript from a PFIS predoctoral scholarship. Conflict of interest: G.M. Lledó reports support for the present manuscript from AGAUR (PANDEMIES 2020). Conflict of interest: A. Agustí reports support for the present manuscript from AGAUR (PANDEMIES 2020). Conflict of interest: J. Sellares reports support for the present manuscript from AGAUR (PANDEMIES 2020); grants or contracts from Boehringer, outside the submitted work; payment or honoraria from Boehringer Roche, Chiesi, Astra and Gebro, outside the submitted work; and support for attending meetings and/or travel from Boehringer and Roche, outside the submitted work. Conflict of interest: O. Sibila reports support for the present manuscript from Menarini, SEPAR, AGAUR (PANDEMIES 2020) and Fons Mecenatge HCB-IDIBAPS. Conflict of interest: R. Faner reports support for the present manuscript from Menarini, SEPAR, AGAUR (PANDEMIES 2020) and Fons Mecenatge HCB-IDIBAPS; grants or contracts from GlaxoSmithKline, AstraZeneca, Instituto de Salud Carlos III, Menarini and the European Research Council, outside the submitted work; consulting fees from GSK, outside the submitted work; and payment or honoraria from Chiesi, outside the submitted work. Conflict of interest: The remaining authors have nothing to disclose.

References

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