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Case Reports
. 2023 May 1;9(6):FSO860.
doi: 10.2144/fsoa-2022-0086. eCollection 2023 Jul.

The unusual finding of peripheral lymphadenopathy among confirmed Lassa fever patients in Nigeria

Sampson O Owhin  1 , Chukuyem Abejegah  1 , Lanre O Olatunde  1 , Nelson A Adedosu  1 , Olufemi O Ayodeji  1 , Timothy R Folorunso  1 , Joachim Azegbeobor  1 , Peter E Akhideno  2 , George O Akpede  2 , Joseph A Ayeyemi  1 , Oyebanji Z Olowosusi  1 , Cyril Erameh  2 , Liasu A Ahmed  1
Affiliations
Case Reports

The unusual finding of peripheral lymphadenopathy among confirmed Lassa fever patients in Nigeria

Sampson O Owhin et al. Future Sci OA. .

Abstract

Lassa fever is a viral haemorrhagic fever belonging to the arenaviridae family that is well known to be endemic to West Africa. The clinical presentation of the disease ranges from asymptomatic to fulminant illness. Lymphadenopathy a clinical manifestation of inflammation, infection, or malignancy has not been widely reported in Lassa fever disease. We report two cases of Lassa fever disease presenting with lymphadenopathy.

Keywords: Federal Medical Center Owo (FMCO); Lassa fever; clinical features; lymphadenopathy.

Plain language summary

Enlargement of lymph nodes, is a common symptom of many infections, however it is not commonly mentioned in patients with Lassa fever, a viral hemorrhagic fever that is endemic in West Africa. However, recent research suggests that lymphadenopathy may be underreported in Lassa fever patients. This new finding could have important implications for the diagnosis and treatment of the disease, as well as for our understanding of how it spreads.

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