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Review
. 2023 Jun:7:100099.
doi: 10.1016/j.hsr.2023.100099. Epub 2023 May 18.

Diabetes and deaths of COVID-19 patients: Systematic review of meta-analyses

Affiliations
Review

Diabetes and deaths of COVID-19 patients: Systematic review of meta-analyses

Aakriti Garg et al. Health Sci Rev (Oxf). 2023 Jun.

Abstract

Background: COVID-19 is affecting all kinds of patients including diabetics. This article provides an overview of conducted meta-analyses regarding the effect of diabetes on the deaths of COVID-19 patients.

Methodology: The study was conducted as per preferred reporting items for systematic reviews and meta-analysis (PRISMA) statement.

Data sources: The relevant meta-analyses were searched on PubMed till April 2021 and data was extracted from 24 relevant meta-analyses. The overall estimate was calculated in terms of odds ratio or relative risk with a 95% confidence interval.

Results: A total of 09 meta-analyses showed the association of diabetes with the death of COVID-19 patients and 15 meta-analyses have reported the association of diabetes with other comorbidities in the death of COVID-19 patients. The pooled odds ratio or relative risk has shown a significant association of diabetes alone or its associated comorbidities with deaths of COVID-19 patients.

Conclusion: Patients with diabetes and its associated comorbidities need more monitoring if get SARS-Cov-2 infection to reduce deaths.

Keywords: Covid-19 patients; Diabetes; Meta-analysis; Mortality.

PubMed Disclaimer

Conflict of interest statement

The authors declare that they have no competing interests.

Figures

Fig 1:
Fig. 1
The scheme of selection of meta-analysis.

References

    1. Cui J., Li F., Shi Z.L. Origin and evolution of pathogenic coronaviruses. Nat. Rev. Microbiol. 2019;17(3):181–192. - PMC - PubMed
    1. Al-Qahtani A.A. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2): emergence, history, basic and clinical aspects. Saudi J. Biol. Sci. 2020;27:2531–2538. - PMC - PubMed
    1. WHO . 2020.
    1. Gordon D.E., Jang G.M., Bouhaddou M., Xu J., Obernier K., White K.M., O'Meara M.J., Rezelj V.V., Guo J.Z., Swaney D.L., Tummino T.A., Hü ttenhain R., Kaake R.M., Richards A.L., Tutuncuoglu B., Foussard H., Batra J., Haas K., Modak M., Kim M., et al. A SARS-CoV-2 protein interaction map reveals targets for drug repurposing. Nature. 2020;583:459–468. - PMC - PubMed
    1. Yang X., Yu Y., Xu J., Shu H., Liu H., Wu Y., Zhang L., Yu Z., Fang M., Yu T., Wang Y. Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: a single-centered, retrospective, observational study. Lancet. Respir. Med. 2020:e26. doi: 10.1016/S2213-2600(20)30079-5. DOI: - DOI - PMC - PubMed