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Review
. 2023 May 11;10(5):210.
doi: 10.3390/jcdd10050210.

Correlation between Coronary Artery Disease with Other Arterial Systems: Similar, Albeit Separate, Underlying Pathophysiologic Mechanisms

Alexandru Achim  1   2   3 , Orsolya Ágnes Péter  4 , Mihai Cocoi  1 , Adela Serban  1 , Stefan Mot  1 , Alexandra Dadarlat-Pop  1 , Attila Nemes  3 , Zoltan Ruzsa  3
Affiliations
Review

Correlation between Coronary Artery Disease with Other Arterial Systems: Similar, Albeit Separate, Underlying Pathophysiologic Mechanisms

Alexandru Achim et al. J Cardiovasc Dev Dis. .

Abstract

Atherosclerosis is a multifactorial systemic disease that affects the entire arterial tree, although some areas are more prone to lipid deposits than others. Moreover, the histopathological composition of the plaques differs, and the clinical manifestations are also different, depending on the location and structure of the atherosclerotic plaque. Some arterial systems are correlated with each other more than in that they simply share a common atherosclerotic risk. The aim of this perspective review is to discuss this heterogeneity of atherosclerotic impairment in different arterial districts and to investigate the current evidence that resulted from studies of the topographical interrelations of atherosclerosis.

Keywords: arterial tree; atherosclerosis; carotid artery disease; coronary artery disease; peripheral artery disease; vulnerable plaque.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
The morphological differences between clinically manifest atherosclerotic plaques located in different areas of the arterial system.
Figure 2
Figure 2
Additional renal risk factors (right panel) contributing to an accelerated atherosclerosis in chronic kidney disease patients.
See this image and copyright information in PMC

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