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Review
. 2023 Apr 28;21(5):277.
doi: 10.3390/md21050277.

Marine Aspergillus: A Treasure Trove of Antimicrobial Compounds

Affiliations
Review

Marine Aspergillus: A Treasure Trove of Antimicrobial Compounds

Honghua Li et al. Mar Drugs. .

Abstract

Secondary metabolites from marine organisms are diverse in structure and function. Marine Aspergillus is an important source of bioactive natural products. We reviewed the structures and antimicrobial activities of compounds isolated from different marine Aspergillus over the past two years (January 2021-March 2023). Ninety-eight compounds derived from Aspergillus species were described. The chemical diversity and antimicrobial activities of these metabolites will provide a large number of promising lead compounds for the development of antimicrobial agents.

Keywords: antimicrobial activity; marine Aspergillus; secondary metabolites.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Compounds of Aspergillus sp. derived from marine animals.
Figure 2
Figure 2
Compounds of Aspergillus sp. derived from marine plants.
Figure 3
Figure 3
Compounds of Aspergillus sp. derived from mangroves.
Figure 4
Figure 4
Compounds of Aspergillus sp. derived from algae.
Figure 5
Figure 5
Compounds of Aspergillus sp. derived from corals.
Figure 6
Figure 6
Compounds of Aspergillus sp. derived from sponges.
Figure 7
Figure 7
Compounds of Aspergillus sp. derived from seawater.
Figure 8
Figure 8
Compounds of Aspergillus sp. derived from marine sediments.
Figure 9
Figure 9
The proportion of Aspergillus from different marine sources.
Figure 10
Figure 10
The proportion of Aspergillus compounds from different marine sources.

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References

    1. Li C.S., Liu L.T., Yang L., Li J., Dong X. Chemistry and bioactivity of marine-derived bisabolane sesquiterpenoids: A review. Front. Chem. 2022;10:881767. doi: 10.3389/fchem.2022.881767. - DOI - PMC - PubMed
    1. Carroll A.R., Copp B.R., Davis R.A., Keyzers R.A., Prinsep M.R. Marine natural products. Nat. Prod. Rep. 2020;37:175–223. doi: 10.1039/C9NP00069K. - DOI - PubMed
    1. Liu L.L., Wu C.H., Qian P.Y. Marine natural products as antifouling molecules—A mini-review (2014–2020) Biofouling. 2020;36:1210–1226. doi: 10.1080/08927014.2020.1864343. - DOI - PubMed
    1. Cardoso J., Nakayama D.G., Sousa E., Pinto E. Marine-derived compounds and prospects for their antifungal application. Molecules. 2020;25:5856. doi: 10.3390/molecules25245856. - DOI - PMC - PubMed
    1. Bian C., Wang J., Zhou X., Wu W., Guo R. Recent advances on marine alkaloids from sponges. Chem. Biodivers. 2020;17:e2000186. doi: 10.1002/cbdv.202000186. - DOI - PubMed

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