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. 2023 Jul;30(4):333-336.
doi: 10.1007/s40292-023-00581-6. Epub 2023 May 26.

Pre-stroke Adherence to Hypertension Medications in a Bi-racial United States Stroke Belt

Askiel Bruno  1 , Jayachandra Muppa  2 , Iagn Niño Kenji Cabahug  3
Affiliations

Pre-stroke Adherence to Hypertension Medications in a Bi-racial United States Stroke Belt

Askiel Bruno et al. High Blood Press Cardiovasc Prev. 2023 Jul.

Abstract

Introduction: Blood pressure is not optimally reduced in 3 of 4 patients with hypertension (HTN) in the United States.

Aim: We analyzed for factors associations with premorbid non-adherence to HTN medications in acute stroke patients.

Methods: This cross-sectional study included 225 acute stroke patients with self-reported adherence to HTM medications in a stroke registry in the Southeastern United States. We defined medication non-adherence as < 90% of prescribed. Logistic regression analyzed demographic and socioeconomic factors for prediction of adherence.

Results: There were 145 (64%) patients with adherence and 80 (36%) with non-adherence. The likelihood of adherence to HTN medications was decreased among black patients, OR 0.49 (95% CI 0.26-0.93), p = 0.03, and those without health insurance, OR 0.29 (95% CI 0.13-0.64), p = 0.002. Specific reasons for non-adherence were high medication cost in 26 (33%), side effects in 8 (10%), and other unspecified reasons in 46 (58%) patients.

Conclusion: In this study, adherence to HTN medications was significantly lower among black patients and those without health insurance.

Keywords: Antihypertensives; Causes of non-compliance; Medication compliance; Stroke.

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