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Review
. 2023 May 10:14:1154167.
doi: 10.3389/fphar.2023.1154167. eCollection 2023.

Traditional Chinese medicine for heart failure with preserved ejection fraction: clinical evidence and potential mechanisms

Yujian Fan  1 , Zhihua Yang  1   2 , Lin Wang  1 , Yangxi Liu  1 , Yulong Song  1 , Yu Liu  1 , Xianliang Wang  1 , Zhiqiang Zhao  1 , Jingyuan Mao  1
Affiliations
Review

Traditional Chinese medicine for heart failure with preserved ejection fraction: clinical evidence and potential mechanisms

Yujian Fan et al. Front Pharmacol. .

Abstract

Heart failure with preserved ejection fraction accounts for a large proportion of heart failure, and it is closely related to a high hospitalization rate and high mortality rate of cardiovascular disease. Although the methods and means of modern medical treatment of HFpEF are becoming increasingly abundant, they still cannot fully meet the clinical needs of HFpEF patients. Traditional Chinese medicine is an important complementary strategy for the treatment of diseases in modern medicine, and it has been widely used in clinical research on HFpEF in recent years. This article reviews the current situation of HFpEF management, the evolution of guidelines, the clinical evidence and the mechanism of TCM in the treatment of HFpEF. The purpose of this study is to explore the application of TCM for HFpEF, to further improve the clinical symptoms and prognosis of patients and to provide a reference for the diagnosis and treatment of the disease.

Keywords: cardiovascular disease; clinical evidence; heart failure with preserved ejection fraction; potential mechanisms; traditional Chinese medicine.

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Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Figures

FIGURE 1
FIGURE 1
Evolution of guidelines for HFpEF.
FIGURE 2
FIGURE 2
Clinical evidence of TCM for HFpEF.
FIGURE 3
FIGURE 3
Potential mechanisms of TCM for HFpEF.
See this image and copyright information in PMC

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