Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2023 Oct;82(8):692-695.
doi: 10.1007/s00393-023-01370-1. Epub 2023 May 26.

Peripheral T-cell lymphoma mimicking granulomatosis with polyangiitis

Elif Durak Ediboğlu  1 , Dilek Solmaz  2 , Sermin Özkal  3 , Nezahat Karaca Erdoğan  4 , Servet Akar  5
Affiliations

Peripheral T-cell lymphoma mimicking granulomatosis with polyangiitis

Elif Durak Ediboğlu et al. Z Rheumatol. 2023 Oct.

Abstract
in English, German

Upper respiratory tract involvement is common in patients with granulomatosis with polyangiitis (GPA), but malignancies should be kept in mind in the differential diagnosis. A 68-year-old man was referred to rheumatology to investigate for GPA after nasal excisional biopsy. After careful radiologic and pathologic assessment, he was diagnosed with peripheral T‑cell lymphoma, nasal type. This is a rare case of T‑cell lymphoma in a patient who was referred as GPA.

Die Beteiligung des oberen Respirationstrakts tritt häufig auf bei Patienten, die an einer Granulomatose mit Polyangiitis (GPA) leiden, jedoch sollte man bei der Differenzialdiagnose auch an Malignome denken. In der vorliegenden Kasuistik wurde ein 68-jähriger Mann zur Abklärung einer GPA nach nasaler Exzisionsbiopsie an die Rheumatologie überwiesen. Nach sorgfältiger radiologischer und pathologischer Untersuchung wurde bei ihm die Diagnose eines peripheren T‑Zell-Lymphoms vom nasalen Typ gestellt. Hiermit handelt es sich um den seltenen Fall eines T‑Zell-Lymphoms bei einem Patienten, der wegen GPA überwiesen wurde.

Keywords: Biopsy; Granulomatosis with polyangiitis; Lymphoma, T-Cell; Neoplasms; Pathology.

PubMed Disclaimer

References

    1. Martinez Del Pero M, Rasmussen N, Chaudhry A, Jani P, Jayne D (2013) Structured clinical assessment of the ear, nose and throat in patients with granulomatosis with polyangiitis (Wegener’s). Eur Arch Otorhinolaryngol 270(1):345–354. https://doi.org/10.1007/s00405-012-2110-8 - DOI - PubMed
    1. Stone JH (2003) Limited versus severe Wegener’s granulomatosis: baseline data on patients in the Wegener’s granulomatosis etanercept trial. Arthritis Rheum 48:2299–2309 - DOI - PubMed
    1. Jennings CR, Jones NS, Dugar J, Powell RJ, Lowe J (1998) Wegener’s granulomatosis—a review of diagnosis and treatment in 53 subjects. Rhinology 36:188–191 - PubMed
    1. Martinez Del Pero M, Rasmussen N, Chaudhry A, Jani P, Jayne D (2013) Structured clinical assessment of the ear, nose and throat in patients with granulomatosis with polyangiitis (Wegener’s). Eur Arch Otorhinolaryngol 270:345–354 - DOI - PubMed
    1. McDonald TJ, DeRemee RA (1993) Head and neck involvement in Wegener’s granulomatosis (WG). Adv Exp Med Biol 336:309–313 - DOI - PubMed

LinkOut - more resources