Nifedipine and flunarizine block amphetamine-induced behavioral stimulation in mice
- PMID: 3724362
- DOI: 10.1016/0024-3205(86)90605-3
Nifedipine and flunarizine block amphetamine-induced behavioral stimulation in mice
Abstract
Sixteen calcium channel inhibitors (CCI's) were tested in a model utilizing amphetamine-induced behavioral stimulation in mice. Nifedipine, flunarizine and possibly PY 108-068 were effective in blocking amphetamine-induced locomotor stimulation. Verapamil, diltiazem and many other CCI's were ineffective in this experimental paradigm.
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