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Comment

. 2023 Jul;4(7):928-929.

doi: 10.1038/s43018-023-00567-2.

CD4⁺ CAR T cells - more than helpers

M Eric Kohler^{1

2}, Terry J Fry^{3

4}

Affiliations

Affiliations

¹ Department of Pediatrics, University of Colorado Anschutz Medical Campus, Aurora, CO, USA. mark.kohler@cuanschutz.edu.
² Center for Cancer and Blood Disorders, Children's Hospital Colorado, Aurora, CO, USA. mark.kohler@cuanschutz.edu.
³ Department of Pediatrics, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
⁴ Center for Cancer and Blood Disorders, Children's Hospital Colorado, Aurora, CO, USA.

PMID: 37248396
DOI: 10.1038/s43018-023-00567-2

Comment

CD4⁺ CAR T cells - more than helpers

M Eric Kohler et al. Nat Cancer. 2023 Jul.

. 2023 Jul;4(7):928-929.

doi: 10.1038/s43018-023-00567-2.

Authors

M Eric Kohler^{1

2}, Terry J Fry^{3

4}

Affiliations

¹ Department of Pediatrics, University of Colorado Anschutz Medical Campus, Aurora, CO, USA. mark.kohler@cuanschutz.edu.
² Center for Cancer and Blood Disorders, Children's Hospital Colorado, Aurora, CO, USA. mark.kohler@cuanschutz.edu.
³ Department of Pediatrics, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
⁴ Center for Cancer and Blood Disorders, Children's Hospital Colorado, Aurora, CO, USA.

PMID: 37248396
DOI: 10.1038/s43018-023-00567-2

No abstract available

PubMed Disclaimer

Comment on

Tumor-intrinsic sensitivity to the pro-apoptotic effects of IFN-γ is a major determinant of CD4⁺ CAR T-cell antitumor activity.
Boulch M, Cazaux M, Cuffel A, Guerin MV, Garcia Z, Alonso R, Lemaître F, Beer A, Corre B, Menger L, Grandjean CL, Morin F, Thieblemont C, Caillat-Zucman S, Bousso P. Boulch M, et al. Nat Cancer. 2023 Jul;4(7):968-983. doi: 10.1038/s43018-023-00570-7. Epub 2023 May 29. Nat Cancer. 2023. PMID: 37248395 Free PMC article.

References

1. Melenhorst, J. J. et al. Nature 602, 503–509 (2022). - DOI - PubMed - PMC
1. Oh, D. Y. & Fong, L. Immunity 54, 2701–2711 (2021). - DOI - PubMed - PMC
1. Ridge, J. P., Di Rosa, F. & Matzinger, P. Nature 393, 474–478 (1998). - DOI - PubMed
1. Boulch, M. et al. Sci. Immunol. 6, eabd4344 (2021). - DOI - PubMed
1. Borst, J., Ahrends, T., Bąbała, N., Melief, C. J. M. & Kastenmüller, W. Nat. Rev. Immunol. 18, 635–647 (2018). - DOI - PubMed

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