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Comment
. 2023 Jun;55(6):912-913.
doi: 10.1038/s41588-023-01413-y.

Genetic and biological insights into spontaneous coronary artery dissection

No authors listed
Comment

Genetic and biological insights into spontaneous coronary artery dissection

No authors listed. Nat Genet. 2023 Jun.
No abstract available

PubMed Disclaimer

Comment on

  • Genome-wide association meta-analysis of spontaneous coronary artery dissection identifies risk variants and genes related to artery integrity and tissue-mediated coagulation.
    Adlam D, Berrandou TE, Georges A, Nelson CP, Giannoulatou E, Henry J, Ma L, Blencowe M, Turley TN, Yang ML, Chopade S, Finan C, Braund PS, Sadeg-Sayoud I, Iismaa SE, Kosel ML, Zhou X, Hamby SE, Cheng J, Liu L, Tarr I, Muller DWM, d'Escamard V, King A, Brunham LR, Baranowska-Clarke AA, Debette S, Amouyel P, Olin JW, Patil S, Hesselson SE, Junday K, Kanoni S, Aragam KG, Butterworth AS; CARDIoGRAMPlusC4D; MEGASTROKE; International Stroke Genetics Consortium (ISGC) Intracranial Aneurysm Working Group; Tweet MS, Gulati R, Combaret N; DISCO register; Kadian-Dodov D, Kalman JM, Fatkin D, Hingorani AD, Saw J, Webb TR, Hayes SN, Yang X, Ganesh SK, Olson TM, Kovacic JC, Graham RM, Samani NJ, Bouatia-Naji N. Adlam D, et al. Nat Genet. 2023 Jun;55(6):964-972. doi: 10.1038/s41588-023-01410-1. Epub 2023 May 29. Nat Genet. 2023. PMID: 37248441 Free PMC article.

References

    1. Hayes, S. N. et al. Spontaneous coronary artery dissection: JACC state-of-the-art review. J. Am. Coll. Cardiol. 76, 961–984 (2020). A review article that describes the clinical presentation of SCAD. - DOI - PubMed
    1. Margaritis, M. et al. Vascular histopathology and connective tissue ultrastructure in spontaneous coronary artery dissection: pathophysiological and clinical implications. Cardiovasc. Res. 118, 1835–1848 (2022). A description of the histopathology of SCAD. - DOI - PubMed
    1. Carss, K. J. et al. Spontaneous coronary artery dissection: insights on rare genetic variation from genome sequencing. Circ. Genom. Precis. Med. 13, e003030 (2020). A sequencing study that investigates the frequency of potential causal rare genetic variants in SCAD. - DOI - PubMed - PMC
    1. Amrani-Midoun, A., Adlam, D. & Bouatia-Naji, N. Recent advances on the genetics of spontaneous coronary artery dissection. Circ. Genom. Precis. Med. 14, e003393 (2021). A review article on the genetic basis of SCAD involving rare and common variants. - DOI - PubMed
    1. Saw, J. et al. Spontaneous coronary artery dissection: clinical outcomes and risk of recurrence. J. Am. Coll. Cardiol. 70, 1148–1158 (2017). An observational study that describes an association between hypertension and SCAD recurrence. - DOI - PubMed

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