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. 1979 Jan;110(1):61-6.
doi: 10.1099/00221287-110-1-61.

Uroporphyrin- and coproporphyrin I-accumulating mutant of Escherichia coli K12

Uroporphyrin- and coproporphyrin I-accumulating mutant of Escherichia coli K12

P Chartrand et al. J Gen Microbiol. 1979 Jan.

Abstract

A new type of haem-deficient mutant was isolated in Escherichia coli K12 by neomycin selection. The mutant was deficient in uroporphyrinogen III cosynthase activity as indicated by the accumulation of uroporphyrin I and coproporphyrin. The mapping of the corresponding hemD gene by P1-mediated transduction showed that the new gene was located between ilv and cya, at min 83 on the chromosomal map of Escherichia coli K12.

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