Uroporphyrin- and coproporphyrin I-accumulating mutant of Escherichia coli K12
- PMID: 372493
- DOI: 10.1099/00221287-110-1-61
Uroporphyrin- and coproporphyrin I-accumulating mutant of Escherichia coli K12
Abstract
A new type of haem-deficient mutant was isolated in Escherichia coli K12 by neomycin selection. The mutant was deficient in uroporphyrinogen III cosynthase activity as indicated by the accumulation of uroporphyrin I and coproporphyrin. The mapping of the corresponding hemD gene by P1-mediated transduction showed that the new gene was located between ilv and cya, at min 83 on the chromosomal map of Escherichia coli K12.