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Case Reports
. 2023 Feb 27:44:108.
doi: 10.11604/pamj.2023.44.108.37603. eCollection 2023.

Ovarian plasmacytoma: a case report

Anass Haloui  1 , Nassira Karich  1 , Nada Akouh  1 , Noura Seghrouchni  1 , Younesse Najioui  1 , Asmae Aissaoui  1 , El Mehdi Tiabi  1 , Samia Malki  1 , Samah Tahri  2 , Houda Bachir  2 , Abbou Widad  3 , Rim Ouajdi  3 , Imane Kamaoui  3 , Mhand Mohammed  4 , Badr Serji  4 , Tijani Elharroudi  4 , Amal Bennani  1
Affiliations
Case Reports

Ovarian plasmacytoma: a case report

Anass Haloui et al. Pan Afr Med J. .

Abstract

Plasmacytomas are a rare spectrum of plasma cell neoplasms that are single localized tumours, lacking the clinical features of plasma cell myeloma with no radiographical evidence of additional plasma cell tumours. Two clinical variants of plasmacytomas can be distinguished: solitary plasmacytoma of bone and extramedullary (or extraosseous) plasmacytoma. The latter is rare, representing 1% of all plasma cell neoplasms, occurring most frequently in the upper airways. Ovarian localization is exceptional, with only a few cases being reported in the literature. We herein report a case of an ovarian extramedullary plasmacytoma occurring in a 56-year-old woman who consulted for abdominal pain and abdominal mass, while highlighting the main histological and immunohistochemical features of this rare malignancy, along with a thorough review of literature gathering all cases of ovarian plasmacytomas reported to date.

Keywords: Extramedullary plasmacytoma; case report; ovary; plasma cell neoplasm.

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Conflict of interest statement

The authors declare no competing interests.

Figures

Figure 1
Figure 1
abdominal-pelvic CT scan showing an oval, well-limited right ovarian mass, with a prevailing cystic component and a solid component enhanced after injection of contrast agent
Figure 2
Figure 2
low power view showing a tumoral proliferation arranged in a well limited nodule within the ovarian cyst´s wall (hematoxylin and eosin stain, magnification x4)
Figure 3
Figure 3
high power view showing diffuse sheets of tumoral cell displaying a plasmacytoid morphology, with rounded eccentric nucleus, coarse clumped chromatin, and abundant eosinophilic cytoplasm (hematoxylin and eosin stain, magnification x40)
Figure 4
Figure 4
low power view demonstrating diffuse expression of CD138 by the tumoral cells (magnification x4)
Figure 5
Figure 5
high power view showing strong and diffuse membranous expression of CD138 by tumoral cells (magnification x40)
Figure 6
Figure 6
high power view showing patchy membranous and cytoplasmic staining by EMA of the tumoral cells (magnification x40)
Figure 7
Figure 7
Ki67 estimated at 80%
See this image and copyright information in PMC

References

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