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Case Reports
. 2023 Apr 27;15(4):e38195.
doi: 10.7759/cureus.38195. eCollection 2023 Apr.

Osteosarcoma of the Proximal Fibula: A Case Report and Review of the Literature

Affiliations
Case Reports

Osteosarcoma of the Proximal Fibula: A Case Report and Review of the Literature

Oğuzhan Muslu et al. Cureus. .

Abstract

Osteosarcoma is the most common primary malignant bone tumor, especially in younger patients. Diagnosis is based on the combined evaluation of radiological, clinical, and pathological examinations. It is usually located in the distal femur, proximal tibia, and proximal humerus. The fibula is a rare localization for osteosarcoma. Surgery in this region is challenging due to the complex anatomic structures around the knee. Especially the peroneal nerve, lateral collateral ligament (LCL), and popliteal vessel branches are of critical importance. However, additional structures such as the arcuate ligament, biceps femoris, and iliotibial band play an essential role in the stabilization of the knee. Thus, these structures must be protected as much as possible. This case report aims to present the diagnosis and treatment process of conventional osteosarcoma in the proximal fibula, which was located close to the peroneal nerve and required LCL reconstruction after the resection.

Keywords: lateral collateral ligament; osteosarcoma; peroneal nerve; primary bone neoplasm; proximal fibula.

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Conflict of interest statement

The authors have declared that no competing interests exist.

Figures

Figure 1
Figure 1. Direct radiograph of the patient who presented with complaints of pain and swelling in the right knee
A lesion can be seen containing opacities and showing a periosteal reaction, which was destroying the cortex in the proximal fibula.
Figure 2
Figure 2. MRI showing a mass consistent with osteosarcoma localized in the proximal fibula and showing soft tissue expansion
Figure 3
Figure 3. Wide resection was performed to the proximal fibula, preserving the peroneal nerve.
Figure 4
Figure 4. Radiograph of the patient at the one-month postoperative follow-up

References

    1. Nielsen GP, Rosenberg AE. Diagnostic pathology: bone. USA: Elsevier; 2021. Diagnostic Pathology: Bone.
    1. En bloc resection of osteosarcoma of the proximal fibula. An analysis of 8 cases. Saini R, Bali K, Gill SS, Mootha AK, Dhillon MS. https://pubmed.ncbi.nlm.nih.gov/21302580/ Acta Orthop Belg. 2010;76:806–810. - PubMed
    1. Yıldız Y. Multidisipliner Yaklaşımla Kemik ve Yumuşak Doku Tümörleri (Article in Turkish) Ankara, Turkey: Turkish Orthopedics and Traumatology Association; 2013. Osteosarkoma; pp. 201–204.
    1. Osteosarcoma (osteogenic sarcoma) Picci P. Orphanet J Rare Dis. 2007;2:6. - PMC - PubMed
    1. Osteosarcoma of the proximal fibula. An analysis of 13 cases in the northern Japan. Takahashi S, Ogose A, Tajino T, Osanai T, Okada K. Ups J Med Sci. 2007;112:366–372. - PubMed

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