Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Editorial
. 2023 May 1;7(5):380-383.
doi: 10.4049/immunohorizons.2300032.

Negative Data, Oh No What Should I Do? How Publication of Negative Data Removes Roadblocks to Productive Research from the Perspective of Scientists Who Perform the Experiments

Angela K Beltrame  1   2 , Johnathon J Caldon  1   2 , Cody J Gurski  1 , Zivar Hajiyeva  1 , Nathan J Meinhardt  1   2 , Kelli C Sommers  1   2 , Savannah D Neu  1   2 , Bonnie N Dittel  1   2
Affiliations
Editorial

Negative Data, Oh No What Should I Do? How Publication of Negative Data Removes Roadblocks to Productive Research from the Perspective of Scientists Who Perform the Experiments

Angela K Beltrame et al. Immunohorizons. .
No abstract available

PubMed Disclaimer

Figures

FIGURE 1.
FIGURE 1.
Publication of negative data removes roadblocks that lead to a scientific dead end. This schematic shows the possible routes of a new scientist approaching a research question with and without the publication of negative data. Without the negative data, the roads to known dead ends are still open, potentially causing that scientist to turn off course. Alternatively, with publishing negative data, those roads can be closed, allowing the scientist to direct their travel to new roads with unknown answers.
See this image and copyright information in PMC

References

    1. Gurski, C. J., Dittel B. N.. 2022. Myeloperoxidase as a marker to differentiate mouse monocyte/macrophage subsets. J. Mol. Sci. 23: 8246. - PMC - PubMed
    1. Aratani, Y. 2018. Myeloperoxidase: its role for host defense, inflammation, and neutrophil function. Arch. Biochem. Biophys. 640: 47–52. - PubMed
    1. Sunderkötter, C., Nikolic T., Dillon M. J., Van Rooijen N., Stehling M., Drevets D. A., Leenen P. J.. 2004. Subpopulations of mouse blood monocytes differ in maturation stage and inflammatory response. J. Immunol. 172: 4410–4417. - PubMed
    1. Kimball, A., Schaller M., Joshi A., Davis F. M., denDekker A., Boniakowski A., Bermick J., Obi A., Moore B., Henke P. K., et al. . 2018. Ly6CHi blood monocyte/macrophage drive chronic inflammation and impair wound healing in diabetes mellitus. Arterioscler. Thromb. Vasc. Biol. 38: 1102–1114. - PMC - PubMed
    1. Rose, S., Misharin A., Perlman H.. 2012. A novel Ly6C/Ly6G-based strategy to analyze the mouse splenic myeloid compartment. Cytometry A 81: 343–350. - PMC - PubMed

Publication types

LinkOut - more resources