An intoxication involving 2-methyl AP-237 and AP-238 from Victoria, Australia: Case report

Jacqueline Maplesden¹, Shaun Greene^{2

3

4}, Rebekka Syrjanen^{3

5}, Matthew Di Rago⁶, Jennifer Schumann^{5

6

7}

Affiliations

¹ Department of Emergency Medicine, St Vincent's Hospital, Melbourne, Australia.
² Department of Emergency Medicine, Austin Hospital, Melbourne, Australia.
³ Victorian Poisons Information Centre, Austin Health, Melbourne, Australia.
⁴ Department of Critical Care, University of Melbourne, Melbourne, Australia.
⁵ Department of Forensic Medicine, Monash University, Melbourne, Australia.
⁶ Victorian Institute of Forensic Medicine, Monash University, Melbourne, Australia.
⁷ Monash Addiction Research Centre, Melbourne, Australia.

Case Reports

Jacqueline Maplesden et al. Drug Test Anal. 2024 Jan.

. 2024 Jan;16(1):93-98.

doi: 10.1002/dta.3524. Epub 2023 May 30.

Jacqueline Maplesden¹, Shaun Greene^{2

3

4}, Rebekka Syrjanen^{3

5}, Matthew Di Rago⁶, Jennifer Schumann^{5

6

7}

¹ Department of Emergency Medicine, St Vincent's Hospital, Melbourne, Australia.
² Department of Emergency Medicine, Austin Hospital, Melbourne, Australia.
³ Victorian Poisons Information Centre, Austin Health, Melbourne, Australia.
⁴ Department of Critical Care, University of Melbourne, Melbourne, Australia.
⁵ Department of Forensic Medicine, Monash University, Melbourne, Australia.
⁶ Victorian Institute of Forensic Medicine, Monash University, Melbourne, Australia.
⁷ Monash Addiction Research Centre, Melbourne, Australia.

No abstract available

References

1. United Nations Office on Drugs and Crime (UNODC). World drug report 2021. 2021. https://www.unodc.org/unodc/data-and-analysis/wdr2021.html Accessed 1 May 2023.
1. Resnik K, Brandao P, Alves EA. DARK classics in chemical neuroscience: bucinnazine. ACS Chem Nerosci. 2021;12(19):3527-3534. doi:10.1021/acschemneuro.1c00522
1. National Forensic Laboratory Slovenia. Analytical report 2-methyl AP-237 (C18H26N20). 19 March 2019. https://www.deadiversion.usdoj.gov/dea_tox/announcements/2-Methyl_AP-237... Accessed 1 May 2023.
1. European Monitoring Centre for Drugs and Drug Addiction (EMCDDA). European drug report 2020. 2020. https://www.emcdda.europa.eu/system/files/publications/13236/TDAT20001EN... Accessed 17 July 2022.
1. Fogarty MF, Vandeputte MM, Krotulski AJ, et al. Toxicological and pharmacological characterization of novel cinnamylpiperazine synthetic opioids in humans and in vitro including 2-methyl AP-237 and AP-238. Arch Toxicol. 2022;96(6):1701-1710. doi:10.1007/s00204-022-03257-7