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. 2023 Aug;14(4):625-632.
doi: 10.1007/s41999-023-00777-y. Epub 2023 May 31.

STOPP/START criteria for potentially inappropriate prescribing in older people: version 3

Denis O'Mahony  1   2 , Antonio Cherubini  3 , Anna Renom Guiteras  4 , Michael Denkinger  5 , Jean-Baptiste Beuscart  6 , Graziano Onder  7 , Adalsteinn Gudmundsson  8 , Alfonso J Cruz-Jentoft  9 , Wilma Knol  10 , Gülistan Bahat  11 , Nathalie van der Velde  12 , Mirko Petrovic  13 , Denis Curtin  14
Affiliations

STOPP/START criteria for potentially inappropriate prescribing in older people: version 3

Denis O'Mahony et al. Eur Geriatr Med. 2023 Aug.

Erratum in

Abstract

Purpose: STOPP/START is a physiological systems-based explicit set of criteria that attempts to define the clinically important prescribing problems relating to potentially inappropriate medications (PIMs-STOPP criteria) and potential prescribing omissions (PPOs-START criteria). The previous two versions of STOPP/START criteria were published in 2008 and 2015. The present study describes the revised and updated third version of the criteria.

Methods: A detailed system-by-system review of the published literature from April 2014 to March 2022 was undertaken with the aim of including clinically important new explicit PIM and PPO criteria and removing any criteria considered to be no longer correct or outdated. A panel of 11 academic physicians with recognized expertise in geriatric pharmacotherapy from 8 European countries participated in a Delphi panel with the task of validating the draft criteria. The panel was presented with the draft new criteria using the SurveyMonkey® on-line platform in which panelists were asked to indicate their level of agreement on a five-point Likert scale.

Results: Two hundred and four evidence-based draft criteria (one hundred and forty-five STOPP criteria, fifty-nine START criteria) were presented to panelists for assessment using the Delphi validation method. Over the course of four rounds of Delphi validation, the panel achieved consensus on 133 STOPP criteria and 57 START criteria, i.e., 190 STOPP/START criteria in total representing a 66.7% increase in the number of criteria compared to STOPP/START version 2 published in 2015.

Conclusion: A fully revised and updated version of STOPP/START criteria has been validated by a European expert panel using the Delphi consensus process.

Keywords: Adverse drug events; Medication review; Multimorbidity; Older people; Polypharmacy; STOPP/START criteria.

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Conflict of interest statement

On behalf of all authors, the corresponding author states that there is no conflict of interest.

Figures

Fig. 1
Fig. 1
Flow diagram depicting Delphi validation process for validation of STOPP/START version 3 criteria
See this image and copyright information in PMC

Comment in

References

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