Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2023 May 16:14:956772.
doi: 10.3389/fendo.2023.956772. eCollection 2023.

Effects of TCM on polycystic ovary syndrome and its cellular endocrine mechanism

Huize Chen  1 , Chujun Deng  1 , Zeyu Meng  2 , Shengxi Meng  1
Affiliations
Review

Effects of TCM on polycystic ovary syndrome and its cellular endocrine mechanism

Huize Chen et al. Front Endocrinol (Lausanne). .

Abstract

Polycystic ovary syndrome (PCOS) is a reproductive endocrine disease characterized by menstrual disorders, infertility, and obesity, often accompanied by insulin resistance and metabolic disorders. The pathogenesis of PCOS is relatively complex and has a certain relationship with endocrine disorders. The increase of androgen and luteinizing hormone (LH) is the main cause of a series of symptoms. Traditional Chinese medicine (TCM) has obvious advantages and significant curative effects in the treatment of this disease. It can effectively reduce the insulin level of PCOS patients, regulate lipid metabolism, and increase ovulation rate and pregnancy rate and has fewer side effects. This article reviews the efficacy and safety of Chinese herbs and other TCM (such as acupuncture) in the treatment of PCOS and its complications in recent years, as well as the effect and mechanism on cellular endocrine, in order to provide a new clinical idea for the treatment of PCOS.

Keywords: TCM; cellular endocrinology; mechanism of action; metabolic disorders; polycystic ovary syndrome.

PubMed Disclaimer

Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Figures

Figure 1
Figure 1
Mechanism of TCM treatment of PCOS. TCM ameliorates insulin resistance and improves follicular development via several pathways. TCM, traditional Chinese medicine; PCOS, polycystic ovary syndrome.
See this image and copyright information in PMC

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. Azziz R. Polycystic ovary syndrome. Obstet Gynecol (2018) 132(2):321–36. doi: 10.1097/aog.0000000000002698 - DOI - PubMed
    1. Ding T, Hardiman PJ, Petersen I, Baio G. Incidence and prevalence of diabetes and cost of illness analysis of polycystic ovary syndrome: a Bayesian modelling study. Hum Reprod (2018) 33(7):1299–306. doi: 10.1093/humrep/dey093 - DOI - PubMed
    1. Gadalla MA, Norman RJ, Tay CT, Hiam DS, Melder A, Pundir J, et al. . Medical and surgical treatment of reproductive outcomes in polycystic ovary syndrome: an overview of systematic reviews. Int J Fertil Steril (2020) 13(4):257–70. doi: 10.22074/ijfs.2020.5608 - DOI - PMC - PubMed
    1. Yang S, Gu YY, Jing F, Yu CX, Guan QB. The effect of statins on levels of dehydroepiandrosterone (Dhea) in women with polycystic ovary syndrome: a systematic review and meta-analysis. Med Sci Monitor (2019) 25:590–7. doi: 10.12659/msm.914128 - DOI - PMC - PubMed
    1. Tian Y, Zhao H, Chen HT, Peng YQ, Cui LL, Du YZ, et al. . Variants in fshb are associated with polycystic ovary syndrome and luteinizing hormone level in han Chinese women. J Clin Endocrinol Metab (2016) 101(5):2178–84. doi: 10.1210/jc.2015-3776 - DOI - PubMed

Publication types