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. 2023 May 8;21(4):333-342.
doi: 10.18502/ijrm.v21i4.13272. eCollection 2023 May.

The relationship between dietary micronutrients and endometriosis: A case-control study

Ghazal Roshanzadeh  1 , Shahideh Jahanian Sadatmahalleh  1 , Ashraf Moini  2   3   4 , Azadeh Mottaghi  5 , Farahnaz Rostami  1
Affiliations

The relationship between dietary micronutrients and endometriosis: A case-control study

Ghazal Roshanzadeh et al. Int J Reprod Biomed. .

Abstract

Background: Fewer studies were on micronutrient intake in women with endometriosis, and the etiology of endometriosis remains unclear between dietary micronutrients and the risk of endometriosis.

Objective: This study aimed to investigate the relationship between dietary micronutrients and the risk of endometriosis.

Materials and methods: This case-control study was conducted on 156 women (18-45 yr) with and without endometriosis in the gynecology clinic of Arash hospital between May 2017 and May 2018 in Tehran, Iran. According to the laparoscopic findings, the participants were divided into 2 groups (n = 78/each), women with pelvic endometriosis as the case group and women without endometriosis pelvic as the control group. Dietary data were collected using a validated 168-item semiquantitative food frequency questionnaire with the standard serving. A logistic regression model was used to determine the association between micronutrients and the risk of endometriosis.

Results: Data analysis showed a significant relationship between micronutrients such as: potassium (OR: 0.74; CI: 0.56-0.99; p = 0.01), calcium (OR: 0.70; CI: 0.52-0.94; p = 0.003), and also among the vitamin C (OR: 0.70; CI: 0.52-0.94; p = 0.02), B2 (OR: 0.73; CI: 0.55-0.98; p = 0.01), and B12 (OR: 0.71; CI: 0.53-0.95; p = 0.02) with endometriosis, so those who used fewer micronutrients were at higher risk of endometriosis.

Conclusion: The findings showed that the dietary intakes of calcium, potassium, vitamins B12, B2, B6, and C are inversely related to the risk of endometriosis.

Keywords: Endometriosis; Food questionary; Micronutrients.; Diet.

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Conflict of interest statement

The authors declare that they have no conflict of interest.

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