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Review
. 2023 Apr;77(2):150-154.
doi: 10.5455/medarh.2023.77.150-154.

Myxopapillary Ependymoma-a Case Report of Rare Multicentric Subtype and Literature Review

Faisal R Almatrafi  1 , Abdullah M Aseeri  2 , Mohammad F Alqahtani  3 , Liqa Al Mulla  4 , Saeed Al-Jubran  5 , Majed A AlOmair  2 , Sultan Alsalmi  1 , Rawan Al-Anazi  6
Affiliations
Review

Myxopapillary Ependymoma-a Case Report of Rare Multicentric Subtype and Literature Review

Faisal R Almatrafi et al. Med Arch. 2023 Apr.

Abstract

Background: Myxopapillary ependymoma is a rare type of primary spinal tumor, it is distinctly a slow-growing tumor that originates in the conus medullaris, cauda equina, or film terminals and is rarely identified as a multicentric type. Myxopapillary ependymoma has a unique histological characteristic and is associated with a generally better prognosis.

Objective: We present a case of a rare multicentric myxopapillary ependymoma.

Case presentation: A 28-year-old male with 1-year history of low back pain and 3 months of radiating pain to left lower limb with perianal anesthesia. Magnetic resonance imaging (MRI) exhibited a large intradural intramedullary lesion from the level of the conus medullaris extending to the filum terminals at the level of T12 to L3 with smaller multiple enhancing lesions seen opposite to L4 and L5 level as well as within the exiting nerve roots, at the left side of L1/L2 and L2/L3 and right side of L3/L4 and L5/S1 level. The patient underwent surgical resection with significant improvement in symptoms and no tumor progression on follow up MRI scan.

Conclusion: We hereby present a case of multicentric myxopapillary ependymoma with a literature review of the previous reported cases. We believe that our study will make a significant contribution to the literature and will be of interest to the readership regarding of the rarity of multicentric Myxopapillary ependymoma and it will help in decision making for the proper surgical Intervention on these kinds of cases.

Keywords: Ependymal tumor; Multicentric ependymoma; Multifocal ependymoma; Myxopapillary ependymoma.

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Conflict of interest statement

None declared.

Figures

Figure 1.
Figure 1.. Intense enhancing intradural intra-medullary lesion from the level of the conus medullaris extending to the filum terminalis from the level of T 12 to L3
Figure 2.
Figure 2.. Multiple enhancing lesions are seen opposite to L4 and L5 levels and within the exiting nerve roots, at the left side of LI/L2 and L2/L3 and right side of L3/L4 and L5/Sl levels.
Figure 3.
Figure 3.. A. The low power view shows lesional tissue exhibiting papillary architecture.(Hematoxylin & Eosin, 4x magnification). B & C. The papillae are lined by slightly elongated cells surrounding vascularized myxoid cores.(llematoxylin & Eosin, 20x magnification).
Figure 4.
Figure 4.. Status post laminectomy at Tl 2-L3 level with resection of the lesion extending from T12-L3 with underlying postoperative changes noted in form of subcutaneous surgical tract with enhancing of the thecal sac at the surgical bed as well as enhancing paraspinal soft tissue.
Figure 5.
Figure 5.. Multiple enhancing lesions are seen opposite to L4 and L5 levels and within the exiting nerve roots, at the left side ofLl/L2 and L2/L3 and right side ofL3/L4 and L5/Sl levels.
See this image and copyright information in PMC

References

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