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Randomized Controlled Trial
. 2024 Jan;53(1):51-58.
doi: 10.1007/s00256-023-04373-w. Epub 2023 Jun 2.

Effectiveness of single intra-bursal injection of platelet-rich plasma against corticosteroid under ultrasonography guidance for shoulder impingement syndrome: a randomized clinical trial

Padma Badra Hewavithana  1 , Mihiri Chami Wettasinghe  2 , Gothami Hettiarachchi  1 , Manel Ratnayaka  3 , Hilary Suraweera  4 , Nuwan Darshana Wickramasinghe  5 , Pallegoda Vithanage Ranjith Kumarasiri  6
Affiliations
Randomized Controlled Trial

Effectiveness of single intra-bursal injection of platelet-rich plasma against corticosteroid under ultrasonography guidance for shoulder impingement syndrome: a randomized clinical trial

Padma Badra Hewavithana et al. Skeletal Radiol. 2024 Jan.

Abstract

Objective: To compare the effectiveness of intra-bursal injection of single-dose platelet-rich plasma (PRP) against corticosteroids under ultrasonography guidance in shoulder impingement syndrome (SIS).

Materials and methods: This single-blind randomized controlled trial was conducted on 60 participants with a clinical diagnosis of SIS from a selected orthopedic clinic. Thirty participants in each arm were given a single dose of either PRP or triamcinolone acetonide into the subacromial sub-deltoid bursa (SASD) under ultrasonography guidance. The outcome variables assessed were the severity score of pain and the degree of shoulder abduction. Post-treatment follow-up was done in 1 week, 3 months, 6 months, and 1 year.

Results: At 1 week, the triamcinolone arm showed a statistically significant reduction of pain (p = 0.039) when compared to PRP. In the long term, PRP showed statistically significant improvement in shoulder abduction, compared to the triamcinolone injection (p = 0.012).

Conclusion: PRP and triamcinolone in the SASD bursa could be considered as safe treatment options for SIS under ultrasonography guidance. While triamcinolone was effective in short-term pain reduction, PRP was effective in long-term improvement in shoulder abduction.

Keywords: Platelet-rich plasma; Shoulder impingement; Supraspinatus tendinopathy.

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