Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2023 Jun 1;30(6):743-744.
doi: 10.1016/j.stem.2023.05.011.

Unlocking the secrets of cancer stem cells: Immune checkpoint inhibitors face their formidable foes

Kevin Roarty  1
Affiliations
Free article
Comment

Unlocking the secrets of cancer stem cells: Immune checkpoint inhibitors face their formidable foes

Kevin Roarty. Cell Stem Cell. .
Free article

Abstract

In this issue of Cell Stem Cell, Beziaud et al.1 show that immunotherapy induces stem-like properties in models of breast cancer. Strikingly, T-cell-derived IFNγ promotes cancer stem cell (CSC) phenotypes, therapy resistance, and metastasis. Targeting BCAT1 downstream offers promise for enhancing immunotherapy outcomes.

PubMed Disclaimer

Conflict of interest statement

Declaration of interests The author declares no competing interests.

Comment on

Publication types

Substances

LinkOut - more resources