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. 2023 Jun:100:104166.
doi: 10.1016/j.etap.2023.104166. Epub 2023 Jun 1.

Screening of phthalate and non-phthalate plasticizers and bisphenols in Sicilian women's blood

Giuseppa Di Bella  1 , Miriam Porretti  2 , Mirea Cafarelli  3 , Federica Litrenta  4 , Angela Giorgia Potortì  5 , Vincenzo Lo Turco  6 , Ambrogina Albergamo  7 , Monica Xhilari  8 , Caterina Faggio  9
Affiliations
Free article

Screening of phthalate and non-phthalate plasticizers and bisphenols in Sicilian women's blood

Giuseppa Di Bella et al. Environ Toxicol Pharmacol. 2023 Jun.
Free article

Abstract

The plastic accumulation and its degradation into microplastics is an environmental issue not only for their ubiquity, but also for the release of intrinsic chemicals, such as phthalates (PAEs), non-phthalate plasticizers (NPPs), and bisphenols (BPs), which may reach body organs and tissues, and act as endocrine disruptors. Monitoring plastic additives in biological matrices, such as blood, may help in deriving relationships between human exposure and health outcomes. In this work, the profile of PAEs, NPPs and BPs was determined in Sicilian women's blood with different ages (20-60 years) and interpreted by chemometrics. PAEs (DiBP and DEPH), NPPs (DEHT and DEHA), BPA and BPS were at higher frequencies and greater levels in women's blood and varied in relation to age. According to statistical analysis, younger females' blood had higher contents of plasticizers than older women, probably due to a more frequent use of higher quantities of plastic products in daily life.

Keywords: Bisphenol; Blood; Endocrine disruptor; Non-phthalate plasticizers; Phthalates; Women.

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Conflict of interest statement

Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

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