[Gastrointestinal tract involvement in systemic sclerosis]

Abstract

Gastrointestinal tract involvement in systemic sclerosis concerns more than 90% of patients but is of heterogeneous clinical expression. It can involve the entire intestinal tract and be responsible for multifactorial malnutrition, which is frequent in this disease. It is a major source of deterioration in the quality of life and can even be life-threatening. Management is complex and multidisciplinary, ranging from simple hygienic and dietary measures, to specialized endoscopic or surgical interventional procedures, also including medical treatments, particularly proton pump inhibitors and prokinetics, with potential side effects. Ongoing research for new diagnostic and therapeutic tools promises to improve the management and prognosis of these patients.

Keywords: Chronic intestinal pseudo-obstruction; Colonisation bactérienne chronique du grêle; Ectasie vasculaire antrale gastrique; Gastric antral vascular ectasia; Gastroesophageal reflux disease; Pseudo-obstruction intestinale chronique; Reflux gastro-œsophagien; Sclérodermie systémique; Small intestinal bacterial overgrowth; Systemic sclerosis.