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Review
. 2023 Oct;37(5):925-935.
doi: 10.1016/j.hoc.2023.04.016. Epub 2023 Jun 1.

Prognostic Models in Metastatic Renal Cell Carcinoma

Audreylie Lemelin  1 , Kosuke Takemura  1 , Daniel Y C Heng  2 , Matthew S Ernst  1
Affiliations
Review

Prognostic Models in Metastatic Renal Cell Carcinoma

Audreylie Lemelin et al. Hematol Oncol Clin North Am. 2023 Oct.

Abstract

As many new systemic therapy options have recently emerged, the standard of care for patients with metastatic renal cell carcinoma (mRCC) is gradually changing. The increasing complexity of treatment options requires more personalized treatment strategies. This evolution in the systemic therapy landscape comes with a need for validated stratification models that facilitate decision making and patient counseling for clinicians through a risk-adapted approach. This article summarizes the available evidence on risk stratification and prognostic models for mRCC, including the International mRCC Database Consortium and Memorial Sloan Kettering Cancer Center models, as well as their association with clinical outcomes.

Keywords: Kidney neoplasms; Prognosis; Renal cell carcinoma; Risk stratification.

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