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Editorial
. 2023 Jul;131(1):13-16.
doi: 10.1016/j.bja.2023.05.002. Epub 2023 Jun 2.

Suspected perioperative anaphylaxis: are we making the correct diagnosis?

Didier G Ebo  1 , Marie-Line M van der Poorten  2 , Philip M Hopkins  3
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Free article
Editorial

Suspected perioperative anaphylaxis: are we making the correct diagnosis?

Didier G Ebo et al. Br J Anaesth. 2023 Jul.
Free article

Abstract

We provide a commentary on aspects of a prospective study of the epidemiology of perioperative anaphylaxis in Japan (Japanese Epidemiologic Study for Perioperative Anaphylaxis [JESPA]). Accurate diagnosis of perioperative anaphylaxis is important for research but essential for clinical safety. We evaluate the diagnostic approach used in the JESPA study and caution against over-reliance on diagnostic tests that lack sensitivity and specificity when clinical data suggest an immediate perioperative hypersensitivity reaction is likely.

Keywords: anaphylaxis; basophil activation test; clinical scoring; perioperative anaphylaxis; skin testing; specific IgE; tryptase.

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