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. 2023 Sep;55(9):2155-2160.
doi: 10.1007/s11255-023-03653-7. Epub 2023 Jun 3.

Regional and national burden of prostate cancer: incidence, mortality, years of life lost, and disability-adjusted life years, in Mexico and Latin America from 1990 to 2019

Jose Guzman-Esquivel  1 , Efren Murillo-Zamora  1 , Monica Ortiz-Mesina  2 , Hector R Galvan-Salazar  3 , Luis De-Leon-Zaragoza  4 , Juan C Casarez-Price  4 , Josuel Delgado-Enciso  5 , Ivan Delgado-Enciso  6   7
Affiliations

Regional and national burden of prostate cancer: incidence, mortality, years of life lost, and disability-adjusted life years, in Mexico and Latin America from 1990 to 2019

Jose Guzman-Esquivel et al. Int Urol Nephrol. 2023 Sep.

Abstract

Purpose: Prostate cancer (PC) is the second leading cause of cancer and the fifth cause of cancer-related death. This manuscript aims to determine the incidence, mortality, and Disability Adjusted Life Years (DALYs) trends of PC in the last 30 years in Latin America and Mexico.

Methods: We performed a cross-sectional analysis of a publicly available data set. Data regarding the burden of prostate cancer in 20 Latin-American countries, and the 32 states of Mexico, were retrieved from the Global Burden of Disease Study 2019. Collected information included incidence and mortality rates (per 100,000), as well as the DALYs as absolute numbers and rates (per 100,000) and the annual rates of change in rates from 1990 to 2019.

Results: In Latin America in males aged 55 years or older, the mean incidence rate was 344 cases per 100,000. The number of deaths attributable to prostate cancer observed was 67,110 and the mean mortality rate was 210 per 100,000. The overall burden of disease was 1,120,709 DALYs and the contribution of years of life lost (YLL) was 91.7% ([Formula: see text] = 1,027,946). Mexico presented an incidence rate (279.6) and mortality (99.1) rate (per /100 thousand). In Mexico, 13 states had a DALYs' rate above the national mean (883 per 100,000) and the highest burden (1360 DALYs/100,000) were documented in the state of Guerrero (Southwestern Mexico).

Conclusion: Only two Latin-American countries (Brazil and Colombia) and eight states of Mexico showed a decreased trend about the rate of change of DALYs in the last 30 years.

Keywords: Disability adjusted life years; Incidence; Mexico; Mortality; Prostate cancer.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Fig. 1
Fig. 1
Incidence and mortality rate (per 100 thousand) of prostate cancer in men aged 55 years or older in Latin-American countries, 2019
Fig. 2
Fig. 2
Annual rate of change in the disability-adjusted life years (DALYs) rate (per 100 thousand) due to prostate cancer in men aged 55 years or older, 1990–2019
Fig. 3
Fig. 3
Incidence and mortality rate (per 100 thousand) of prostate cancer in men aged 55 years or older in the states (n = 32) of Mexico, 2019
Fig. 4
Fig. 4
Annual rate of change in the disability-adjusted life years (DALYs) rate (per 100 thousand) due to prostate cancer in the states of Mexico in men aged 55 years or older, 1990–2019
See this image and copyright information in PMC

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