Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Editorial
. 2023 May 18:11:1219294.
doi: 10.3389/fcell.2023.1219294. eCollection 2023.

Editorial: Cell size regulation: molecular mechanisms and physiological importance

Affiliations
Editorial

Editorial: Cell size regulation: molecular mechanisms and physiological importance

Jette Lengefeld et al. Front Cell Dev Biol. .
No abstract available

Keywords: aging; cell cycle; cell growth; cell size; mTOR.

PubMed Disclaimer

Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Figures

FIGURE 1
FIGURE 1
Cell size is determined by the balance between biosynthesis (cell mass accumulation rate) and proliferation (cell division rate). In turn, cell size can affect many important physiological processes—such as proliferation, growth rate, aging, stress response, regeneration, insulin sensitivity, and others. ©BioRender—biorender.com was used for image.

Comment on

  • Editorial on the Research Topic Cell size regulation: molecular mechanisms and physiological importance

References

    1. Cadart C., Monnier S., Grilli J., Sáez P. J., Srivastava N., Attia R., et al. (2018). Size control in mammalian cells involves modulation of both growth rate and cell cycle duration. Nat. Commun. 9, 3275. 10.1038/s41467-018-05393-0 - DOI - PMC - PubMed
    1. Cadart C., Venkova L., Recho P., Lagomarsino M. C., Piel M. (2019). The physics of cell-size regulation across timescales. Nat. Phys. 15, 993–1004. 10.1038/s41567-019-0629-y - DOI
    1. D’Ario M., Tavares R., Schiessl K., Desvoyes B., Gutierrez C., Howard M., et al. (2021). Cell size controlled in plants using DNA content as an internal scale. Science 372, 1176–1181. 10.1126/science.abb4348 - DOI - PubMed
    1. Demidenko Z. N., Blagosklonny M. V. (2008). Growth stimulation leads to cellular senescence when the cell cycle is blocked. Cell. Cycle 7, 3355–3361. 10.4161/cc.7.21.6919 - DOI - PubMed
    1. Ginzberg M. B., Chang N., D’Souza H., Patel N., Kafri R., Kirschner M. W. (2018). Cell size sensing in animal cells coordinates anabolic growth rates and cell cycle progression to maintain cell size uniformity. Elife7 7, e26957. 10.7554/eLife.26957 - DOI - PMC - PubMed

Publication types