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. 2023 Jun;75(2):1221-1225.
doi: 10.1007/s12070-023-03513-x. Epub 2023 Feb 3.

Neurofibrolipoma of Hypopharynx: A Rare Entity

Ravinder Singh Nagi  1 , Rupali  2 , Ruchika Bhagat  3 , Karan Kumar Sharma  4
Affiliations

Neurofibrolipoma of Hypopharynx: A Rare Entity

Ravinder Singh Nagi et al. Indian J Otolaryngol Head Neck Surg. 2023 Jun.

Abstract

A Large pedunculated neurofibrolipoma involving the hypopharynx is a very rare entity. Patient with hypopharyngeal polyp usually presents with progressive dyaphagia, sensation of persistent lump in throat and difficulty in breathing. Regurgitation of the mass into the airway can led to fatal asphyxiation on several occasions and may rarely cause death also if not evaluated and treated timely. Malignant degeneration of these large polyps occurs infrequently. We encountered a case with similar complaints in our outpatient department. After complete clinical examination, radiological investigations and anaesthetic evaluation; patient was taken for elective tracheostomy first and subsequently followed by successful transoral endoscopic excision of hypopharyngeal polypoidal mass. The histopathological examination of mass revealed it to be a neurofibrolipoma.

Keywords: Benign tumours of hypopharynx; Fibrolipomatous hamartoma of nerve; Hypopharyngeal polyp; Lipofibromatosis of nerve; Mesenchymal tumours of pharynx; Neurofibrolipoma.

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Conflict of interest statement

Conflicts of interestThe Authors declare that they have no conflicts of interest to declare that are relevant to the content of this article.

Figures

Fig. 1
Fig. 1
Showing a globular, smooth surfaced pink mass with pedicle (arrow) arising from right side of hypopharynx pushing the epiglottis causing considerable narrowing of the airway on rigid laryngoscopy
Fig. 2
Fig. 2
(A, B) Showing a well-defined, oval hypodense mass lesion (predominantly fat attenuation) in right pharyngeal wall arising from pyriform fossa, extending superiorly in the laryngeal cavity on coronal and sagittal sections of contrast enhanced CT scan respectively
Fig. 3
Fig. 3
(A, B) Images showing approximately 10 cm × 5 cm × 2 cm size of mass excised from pyriform fossa
Fig. 4
Fig. 4
(A, B) Photomicrographs of the histopathology specimen (Hematoxylin and eosin; original and 200 × magnification). The lesion is composed of bundles of spindle cells with fat spaces, fibro-myxoid areas, Blood vessels and nerve bundles, features suggestive of neural fibro lipoma
Fig. 5
Fig. 5
This is 6 months postoperative image showing no residual lesion or any recurrent lesion
See this image and copyright information in PMC

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