Progression of Cardiac Abnormalities in Hutchinson-Gilford Progeria Syndrome: A Prospective Longitudinal Study

Flemming Javier Olsen^{1

2

3}, Leslie B Gordon^{4

2

5}, Leslie Smoot^{1

2}, Monica E Kleinman^{6

4

2}, Marie Gerhard-Herman⁷, Sheila M Hegde⁷, Srinivasan Mukundan⁸, Taylor Mahoney^{9

10}, Joseph Massaro^{9

10}, Sendy Ha¹, Ashwin Prakash^{1

2}

Affiliations

¹ From the Departments of Cardiology (F.J.O., L.S., S.H., A.P.), Boston Children's Hospital and Harvard Medical School, MA.
² Department of Pediatrics, Harvard Medical School, Boston, MA (F.J.O., L.B.G., L.S., M.E.K., A.P.).
³ Department of Cardiology, Copenhagen University Hospital-Herlev and Gentofte, Hellerup, Denmark (F.J.O.).
⁴ Anesthesia (L.B.G., M.E.K.), Boston Children's Hospital and Harvard Medical School, MA.
⁵ Department of Pediatrics, Hasbro Children's Hospital, and Warren Alpert Medical School of Brown University, Providence, RI (L.B.G.).
⁶ Critical Care Medicine (M.E.K.), Boston Children's Hospital and Harvard Medical School, MA.
⁷ Departments of Medicine, Cardiovascular Medicine (M.G.-H., S.M.H.), Brigham and Women's Hospital, Boston, MA.
⁸ Radiology (S.M.), Brigham and Women's Hospital, Boston, MA.
⁹ Department of Mathematics and Statistics, Boston University, MA (T.M., J.M.).
¹⁰ Harvard Clinical Research Institute, Boston, MA (T.M., J.M.).

PMID: 37276254
DOI: 10.1161/CIRCULATIONAHA.123.064370

Progression of Cardiac Abnormalities in Hutchinson-Gilford Progeria Syndrome: A Prospective Longitudinal Study

Flemming Javier Olsen et al. Circulation. 2023.

. 2023 Jun 6;147(23):1782-1784.

doi: 10.1161/CIRCULATIONAHA.123.064370. Epub 2023 Jun 5.

Authors

Affiliations

¹ From the Departments of Cardiology (F.J.O., L.S., S.H., A.P.), Boston Children's Hospital and Harvard Medical School, MA.
² Department of Pediatrics, Harvard Medical School, Boston, MA (F.J.O., L.B.G., L.S., M.E.K., A.P.).
³ Department of Cardiology, Copenhagen University Hospital-Herlev and Gentofte, Hellerup, Denmark (F.J.O.).
⁴ Anesthesia (L.B.G., M.E.K.), Boston Children's Hospital and Harvard Medical School, MA.
⁵ Department of Pediatrics, Hasbro Children's Hospital, and Warren Alpert Medical School of Brown University, Providence, RI (L.B.G.).
⁶ Critical Care Medicine (M.E.K.), Boston Children's Hospital and Harvard Medical School, MA.
⁷ Departments of Medicine, Cardiovascular Medicine (M.G.-H., S.M.H.), Brigham and Women's Hospital, Boston, MA.
⁸ Radiology (S.M.), Brigham and Women's Hospital, Boston, MA.
⁹ Department of Mathematics and Statistics, Boston University, MA (T.M., J.M.).
¹⁰ Harvard Clinical Research Institute, Boston, MA (T.M., J.M.).

PMID: 37276254
DOI: 10.1161/CIRCULATIONAHA.123.064370

No abstract available

Keywords: disease progression; left; progeria; ventricular dysfunction.

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Conflict of interest statement

Disclosures Drs Olsen, Gordon, Smoot, Kleinman, Hegde, Mukundan, Mahoney, Massaro, and Prakash and S. Ha report no disclosures. Dr Gerhard-Herman reports fees paid to the institution for consulting core laboratory services from MyoKardia/Bristol Myers Squibb.

Comment in

Readily Available Tools to Detect Progerin and Cardiac Disease Progression in Hutchinson-Gilford Progeria Syndrome.
Eriksson M, Haugaa K, Revêchon G. Eriksson M, et al. Circulation. 2023 Jun 6;147(23):1745-1747. doi: 10.1161/CIRCULATIONAHA.123.064765. Epub 2023 Jun 5. Circulation. 2023. PMID: 37276251 No abstract available.

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Progression of Cardiac Abnormalities in Hutchinson-Gilford Progeria Syndrome: A Prospective Longitudinal Study

Affiliations

Progression of Cardiac Abnormalities in Hutchinson-Gilford Progeria Syndrome: A Prospective Longitudinal Study

Authors

Affiliations

Conflict of interest statement

Comment in

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MeSH terms