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Book

Tetramine Toxicity

John A. Thompson  1 , B. Zane Horowitz  2
In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan.
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Book

Tetramine Toxicity

John A. Thompson et al.
Free Books & Documents

Excerpt

Tetramethylenedisulfoteramine (tetramine) is a rodenticide that causes severe neurotoxicity. Though internationally banned, tetramine is still manufactured. There are numerous cases of poisoning, especially in rural areas. This agent is available through illicit markets in multiple countries and is relatively inexpensive.

Due to its chemical stability, ease of production, lack of taste or smell, and rapid onset of toxicity, tetramine has been discussed as a possible candidate for a chemical threat agent.

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Conflict of interest statement

Disclosure: John Thompson declares no relevant financial relationships with ineligible companies.

Disclosure: B. Zane Horowitz declares no relevant financial relationships with ineligible companies.

References

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    1. Shakarjian MP, Laukova M, Velíšková J, Stanton PK, Heck DE, Velíšek L. Tetramethylenedisulfotetramine: pest control gone awry. Ann N Y Acad Sci. 2016 Aug;1378(1):68-79. - PMC - PubMed
    1. Zhang Y, Su M, Tian DP. Tetramine poisoning: A case report and review of the literature. Forensic Sci Int. 2011 Jan 30;204(1-3):e24-7. - PubMed
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    1. Barrueto F, Furdyna PM, Hoffman RS, Hoffman RJ, Nelson LS. Status epilepticus from an illegally imported Chinese rodenticide: "tetramine". J Toxicol Clin Toxicol. 2003;41(7):991-4. - PubMed

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