Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2023 Jun 13;120(24):e2302944120.
doi: 10.1073/pnas.2302944120. Epub 2023 Jun 5.

Concern over differences between experimental design and data analyses in Jones et al

Charles V Vorhees  1
Affiliations
Comment

Concern over differences between experimental design and data analyses in Jones et al

Charles V Vorhees. Proc Natl Acad Sci U S A. .
No abstract available

PubMed Disclaimer

Conflict of interest statement

C.V.V. is an independent advisor to the Calorie Control Council, which represents the interests of manufacturers of low- and reduced-calorie foods and beverages.

Comment on

References

    1. Jones S. K., et al. , Transgenerational transmission of aspartame-induced anxiety and changes in glutamate-GABA signaling and gene expression in the amygdala. Proc. Natl. Acad. Sci. U.S.A. 119, e2213120119 (2022). - PMC - PubMed
    1. Lazic S. E., Essioux L., Improving basic and translational science by accounting for litterto-litter variation in animal models. BMC Neurosci. 14, 37 (2013). - PMC - PubMed
    1. Rosso M., et al. , Reliability of common mouse behavioural tests of anxiety: A systematic review and meta-analysis on the effects of anxiolytics. Neurosci. Biobehav. Rev. 143, 104928 (2022). - PubMed
    1. Golub M. S., Sobin C. A., Statistical modeling with litter as a random effect in mixed models to manage "intralitter likeness". Neurotoxicol. Teratol. 77, 106841 (2020). - PubMed
    1. Beck D., Nilsson E. E., Ben Maamar M., Skinner M. K., Environmental induced transgenerational inheritance impacts systems epigenetics in disease etiology. Sci. Rep. 12, 5452 (2022). - PMC - PubMed

LinkOut - more resources