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Comment
. 2023 Jun 8;8(84):eadi8769.
doi: 10.1126/sciimmunol.adi8769. Epub 2023 Jun 2.

Antibody-mediated immunity against lung cancer goes retro

Affiliations
Comment

Antibody-mediated immunity against lung cancer goes retro

Stephanie N Langel et al. Sci Immunol. .

Abstract

Endogenous retrovirus antibody responses contribute to survival after immune checkpoint blockade therapy against lung adenocarcinoma.

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  • Antibodies against endogenous retroviruses promote lung cancer immunotherapy.
    Ng KW, Boumelha J, Enfield KSS, Almagro J, Cha H, Pich O, Karasaki T, Moore DA, Salgado R, Sivakumar M, Young G, Molina-Arcas M, de Carné Trécesson S, Anastasiou P, Fendler A, Au L, Shepherd STC, Martínez-Ruiz C, Puttick C, Black JRM, Watkins TBK, Kim H, Shim S, Faulkner N, Attig J, Veeriah S, Magno N, Ward S, Frankell AM, Al Bakir M, Lim EL, Hill MS, Wilson GA, Cook DE, Birkbak NJ, Behrens A, Yousaf N, Popat S, Hackshaw A; TRACERx Consortium; CAPTURE Consortium; Hiley CT, Litchfield K, McGranahan N, Jamal-Hanjani M, Larkin J, Lee SH, Turajlic S, Swanton C, Downward J, Kassiotis G. Ng KW, et al. Nature. 2023 Apr;616(7957):563-573. doi: 10.1038/s41586-023-05771-9. Epub 2023 Apr 12. Nature. 2023. PMID: 37046094 Free PMC article.

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