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Comment
. 2023 Sep;20(9):522-523.
doi: 10.1038/s41585-023-00788-1.

Doxycycline-PEP - novel and promising but needs monitoring

Magnus Unemo  1   2 , Fabian Yuh Shiong Kong  3
Affiliations
Comment

Doxycycline-PEP - novel and promising but needs monitoring

Magnus Unemo et al. Nat Rev Urol. 2023 Sep.
No abstract available

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Comment on

  • Postexposure Doxycycline to Prevent Bacterial Sexually Transmitted Infections.
    Luetkemeyer AF, Donnell D, Dombrowski JC, Cohen S, Grabow C, Brown CE, Malinski C, Perkins R, Nasser M, Lopez C, Vittinghoff E, Buchbinder SP, Scott H, Charlebois ED, Havlir DV, Soge OO, Celum C; DoxyPEP Study Team. Luetkemeyer AF, et al. N Engl J Med. 2023 Apr 6;388(14):1296-1306. doi: 10.1056/NEJMoa2211934. N Engl J Med. 2023. PMID: 37018493 Free PMC article. Clinical Trial.

References

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    1. Molina, J.-M. et al. Post-exposure prophylaxis with doxycycline to prevent sexually transmitted infections in men who have sex with men: an open-label randomised substudy of the ANRS IPERGAY trial. Lancet Infect. Dis. 18, 308–317 (2018). - DOI - PubMed
    1. Luetkemeyer, A. F. et al. Postexposure doxycycline to prevent bacterial sexually transmitted infections. N. Engl. J. Med. 388, 1296–1306 (2023). - DOI - PubMed
    1. Fiore, M. A., Raisman, J. C., Wong, N. H., Hudson, A. O. & Wadsworth, C. B. Exploration of the Neisseria resistome reveals resistance mechanisms in commensals that may be acquired by N. gonorrhoeae through horizontal gene transfer. Antibiotics 9, 656 (2020). - DOI - PubMed - PMC

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