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. 2023 Aug;202(4):e27-e30.
doi: 10.1111/bjh.18916. Epub 2023 Jun 5.

Effects of pyruvate kinase activators on red blood cell properties in sickle cell disease

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Effects of pyruvate kinase activators on red blood cell properties in sickle cell disease

Philippe Joly et al. Br J Haematol. 2023 Aug.
No abstract available

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References

REFERENCES

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    1. Charache S, Grisolia S, Fiedler AJ, Hellegers AE. Effect of 2,3-diphosphoglycerate on oxygen affinity of blood in sickle cell anemia. J Clin Invest. 1970;49:806-12.
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    1. van Dijk MJ, Rab MAE, van Oirschot BA, Bos J, Derichs C, Rijneveld AW, et al. Safety and efficacy of mitapivat, an oral pyruvate kinase activator, in sickle cell disease: a phase 2, open-label study. Am J Hematol. 2022;97:E226-9.

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