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Case Reports
. 2023 Jun;53(6):1065-1069.
doi: 10.1111/imj.16111. Epub 2023 Jun 6.

The C3 conundrum

Maria Lean  1 , Bobby Chacko  1   2
Affiliations
Case Reports

The C3 conundrum

Maria Lean et al. Intern Med J. 2023 Jun.

Abstract

A 62-year-old man with nephritic syndrome underwent a kidney biopsy which revealed a C3 dominant pattern on immunofluorescence. A diagnosis of C3 glomerulopathy (C3G) was suspected. However, a recent skin infection and high levels of anti-streptococcal antibodies were indicative of post-infectious glomerulonephritis (PIGN). This paper compares PIGN and C3G and describes an atypical form of PIGN with alternative complement pathway dysregulation.

Keywords: C3GN; PIGN; acute glomerulonephritis.

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References

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