Analysis of Differentiation of Hepatocytes and Bile Duct Cells in Developing Mouse Liver by Albumin Immunofluorescence: (albumin distribution/liver cells/differentiation/mouse embryos)
- PMID: 37282105
- DOI: 10.1111/j.1440-169X.1984.00555.x
Analysis of Differentiation of Hepatocytes and Bile Duct Cells in Developing Mouse Liver by Albumin Immunofluorescence: (albumin distribution/liver cells/differentiation/mouse embryos)
Abstract
Differentiation of endodermal cells in embryonic mouse liver was analyzed by study of their albumin immunofluorescence. Hepatocytes extending from the cranial diverticulum in 9.5-day embryos do not contain albumin. In 10.5-to 11.5-day embryos, hepatocytes are still immature, but they all show albumin immunofluorescence. Most precursor cells of intrahepatic bile-duct cells also give a positive reaction for albumin, like immature hepatocytes. The differentiation of intrahepatic bile-duct cells from immature hepatocytes is suggested.
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