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. 2023 Apr;48(8):2068-2076.
doi: 10.19540/j.cnki.cjcmm.20230302.201.

[Research progress of Shegan Mahuang Decoction and predictive analysis on its Q-markers]

[Article in Chinese]
Qiu-Hui Li  1 , Xiao-Xiao Shan  2 , Wei-Dong Ye  1 , Xun-Yan Yin  1 , Ya-Mei Yuan  1 , Xiang-Ming Fang  1
Affiliations

[Research progress of Shegan Mahuang Decoction and predictive analysis on its Q-markers]

[Article in Chinese]
Qiu-Hui Li et al. Zhongguo Zhong Yao Za Zhi. 2023 Apr.

Abstract

Shegan Mahuang Decoction has been used in clinical practice for thousands of years, and is a classical formula for treating asthma and other respiratory diseases, with the effects of ventilating lung, dispersing cold, and relieving cough and asthma. This paper summarized the history, clinical application and mechanism of Shegan Mahuang Decoction, and predicted its quality markers(Q-markers) based on the "five principles" of Q-markers. The results suggested that irisflorentin, tectoridin, tectorigenin, irigenin, ephedrine, pseudoephedrine, asarinin, methyleugenol, shionone, epifriedelanol, tussilagone, 6-gingerol, trigonelline, cavidine, schizandrin, and schizandrin B could be used as Q-markers of Shegan Mahuang Decoction, which provided a basis for the quality control and subsequent research and development of Shegan Mahuang Decoction.

Keywords: Shegan Mahuang Decoction; clinical application; history; mechanism; quality markers.

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