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Case Reports
. 2023 Apr 28:40:50-53.
doi: 10.1016/j.mmcr.2023.04.001. eCollection 2023 Jun.

Persistently elevated intracranial pressure in cryptococcal meningitis- 76 therapeutic lumbar punctures

Samuel Jjunju  1   2 , Edwin Nuwagira  1   2 , David B Meya  2 , Conrad Muzoora  1
Affiliations
Case Reports

Persistently elevated intracranial pressure in cryptococcal meningitis- 76 therapeutic lumbar punctures

Samuel Jjunju et al. Med Mycol Case Rep. .

Abstract

Cryptococcal meningitis still remains the most common form of adult meningitis in sub-Saharan Africa, due to the burden of HIV/AIDS. Increased intracranial pressure (ICP) is a major complication of cryptococcosis and requires aggressive management with therapeutic lumbar punctures (LPs). In this report, we describe a patient with persistently elevated ICP who underwent 76 LPs over 46 days with good outcome. While unusual, this highlights the importance of serial therapeutic LPs. 2012 Elsevier Ltd. All rights reserved.

Keywords: Cryptococcal meningitis; Human Immunodeficiency Virus; Increased intracranial pressure; Lumbar puncture.

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Conflict of interest statement

“There are none”.

Figures

Fig. 1
Fig. 1
A graph representing trend in average daily CSF opening plus closing pressures and volume of CSF drained.
See this image and copyright information in PMC

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