Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2023 May 4;15(5):e38559.
doi: 10.7759/cureus.38559. eCollection 2023 May.

Mollaret's Syndrome: A Case Report

Vivien M Edi  1 , Prasad Rao  1 , Joanna O Igo  2 , Amaka S Odega  3   4   5   6 , Elizabeth Soladoye  7 , Chidalu N Ibeneme  8 , Okelue E Okobi  9   10
Affiliations
Case Reports

Mollaret's Syndrome: A Case Report

Vivien M Edi et al. Cureus. .

Abstract

Benign recurrent aseptic meningitis is a rare condition characterized by recurring, self-limited episodes of aseptic meningitis. Meningeal irritation typically occurs first, accompanied by fever and mononuclear cell pleocytosis. The diagnosis is only made after other known causes of lymphocytic meningitis have been excluded. Resolution typically occurs within two to seven days without residual neurological deficit. Aseptic meningitis is most frequently caused by viruses; Mollaret's meningitis has been linked to the herpes simplex virus 2 (HSV 2). It is unclear if prophylactic medication is indicated for these patients. We describe a patient who was experiencing her seventh episode of aseptic meningitis.

Keywords: mollaret's lymphocytic meningitis; mollaret's meningitis; mollaret's syndrome; rare disease; viral meningitis.

PubMed Disclaimer

Conflict of interest statement

The authors have declared that no competing interests exist.

Figures

Figure 1
Figure 1. Axial and coronal T2W brain MR images showing normal findings
See this image and copyright information in PMC

References

    1. Mollaret’s meningitis: a rare entity. Sehgal A, Pokhrel E, Castro WR, Haas CJ. https://doi.org/10.7759/cureus.15264 Cureus. 2021;13:0. - PMC - PubMed
    1. Toll-like receptor 3 immune deficiency may be causative for HSV-2-associated mollaret meningitis. Willmann O, Ahmad-Nejad P, Neumaier M, Hennerici MG, Fatar M. https://doi.org/10.1159/000287585. Eur Neurol. 2010;63:249–251. - PubMed
    1. Mollaret’s meningitis. Min Z, Baddley JW. https://doi.org/10.1016/s1473-3099(14)70874-6 Lancet. 2014;14:1022. - PubMed
    1. Pierre Mollaret (1898-1987) Vitturi BK, Sanvito WL. https://doi.org/10.1007/s00415-018-8999-0. J Neurol. 2019;266:1290–1291. - PubMed
    1. Pasternack MS. UpToDate. Waltham, MA: UpToDate; [ Jan; 2023 ]. 2022. Approach to the adult with recurrent infections.

Publication types

LinkOut - more resources