Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Editorial
. 2023 Apr 29;8(6):1133-1136.
doi: 10.1016/j.ekir.2023.04.030. eCollection 2023 Jun.

The Interplay Between Dietary Sodium Intake and Proteinuria in CKD

Affiliations
Editorial

The Interplay Between Dietary Sodium Intake and Proteinuria in CKD

Ashish Verma et al. Kidney Int Rep. .
No abstract available

PubMed Disclaimer

Figures

Figure 1
Figure 1
The pathophysiology of sodium-induced CKD progression. CKD, chronic kidney disease.
Figure 2
Figure 2
(a) Mechanism of high dietary sodium intake and kidney disease progression; (b) CKD phenotypes according to dietary sodium intake and urinary protein excretion. CKD, chronic kidney disease; ESKD, end-stage kidney disease; HR, hazard ratio.

Comment on

References

    1. Ellison D.H., Welling P. Insights into salt handling and blood pressure. N Engl J Med. 2021;385:1981–1993. doi: 10.1056/NEJMra2030212. - DOI - PubMed
    1. Kirabo A. A new paradigm of sodium regulation in inflammation and hypertension. Am J Physiol Regul Integr Comp Physiol. 2017;313:R706–R710. doi: 10.1152/ajpregu.00250.2017. - DOI - PMC - PubMed
    1. Wright J.A., Cavanaugh K.L. Dietary sodium in chronic kidney disease: a comprehensive approach. Semin Dial. 2010;23:415–421. doi: 10.1111/j.1525-139X.2010.00752.x. - DOI - PMC - PubMed
    1. Weir M.R., Dengel D.R., Behrens M.T., Goldberg A.P. Salt-induced increases in systolic blood pressure affect renal hemodynamics and proteinuria. Hypertension. 1995;25:1339–1344. doi: 10.1161/01.hyp.25.6.1339. - DOI - PubMed
    1. Weir M.R., Townsend R.R., Fink J.C., et al. Urinary sodium is a potent correlate of proteinuria: lessons from the chronic renal insufficiency cohort study. Am J Nephrol. 2012;36:397–404. doi: 10.1159/000342966. - DOI - PMC - PubMed

LinkOut - more resources