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. 2024 Aug 1;154(2):326e-334e.
doi: 10.1097/PRS.0000000000010816. Epub 2023 Jun 7.

Successful Treatment and Long-Term Follow-Up of Parry-Romberg Syndrome with Anterolateral Thigh Adipofascial Flap

Affiliations

Successful Treatment and Long-Term Follow-Up of Parry-Romberg Syndrome with Anterolateral Thigh Adipofascial Flap

Jingyi Zhao et al. Plast Reconstr Surg. .

Abstract

Background: Anterolateral thigh adipofascial free flap transfer is a frequently used method to reconstruct facial symmetry and restore facial soft-tissue contour in patients with Parry-Romberg syndrome, but long-term prognosis and outcomes are unclear.

Method: The authors report their treatment experience with 42 patients between 2001 and 2017 using microsurgical free anterolateral thigh adipofascial flap transfer. Long-term follow-up results and final reconstructive outcomes were evaluated.

Results: A total of 42 patients were included. The follow-up ranged from 5 to 21 years. All patients were satisfied with the surgery. Photographic evaluation revealed significant enhancement of postoperative appearance. Numbness or hypesthesia of the local area was the most common symptom noted in long-term follow-up.

Conclusions: This study evaluated the long-term results of treating Parry-Romberg disease with microsurgery using ALT free flap in the authors' department. Over 20 years of experience and the significant enhancement in overall appearance indicate a long-lasting, excellent outcome.

Clinical question/level of evidence: Therapeutic, IV.

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References

    1. Parry CH. Collections from the Unpublished Medical Writings of the Late Caleb Hillier Parry MD F.R.S. London: Underwoods; 1825.
    1. Romberg H. Trophoneuronsen. Klinische Ergebnisse. 1846:75–81.
    1. El-Kehdy J, Abbas O, Rubeiz N. A review of Parry Romberg syndrome. J Am Acad Dermatol. 2012;67:769–784.
    1. Zhou G, Qiao Q, Chen GY, Ling YC, Swift R. Clinical experience and surgical anatomy of 32 free anterolateral thigh flap transplantations. Br J Plast Surg. 1991;44:91–96.
    1. Ouf MO, Zayid T, Elbatawy A, et al. Aesthetic restoration of severe hemifacial atrophy with free adipofascial anterolateral thigh flap followed by autologous fat grafting: optimizing result and long-term outcome. J Craniofac Surg. 2021;32:e413–e418.

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