Sequencing checkpoint inhibitor therapy in renal cell carcinoma
- PMID: 37290460
- DOI: 10.1016/S0140-6736(23)01058-9
Sequencing checkpoint inhibitor therapy in renal cell carcinoma
Conflict of interest statement
KEB declares funding to their institution for clinical trials from Aveo, BMS, Exelixis, Arrowhead, Aravive, and Merck; receives research funding to the institution for preclinical research from Aravive, Arsenal, BMS-LCFA-IASLC, and Pionyr; and has received consulting fees from Aveo, BMS, Exelixis, Astrazeneca, Alpine Bioscience, Aravive, Merck, Sanofi, and Seagen, outside the scope of the submitted work. BIR declares institutional funding from Exelixis, AVEO, Genentech, BMS, Arcus, Merck, Dragonfly Therapeutics, HiberCell, Incyte, Stata Oncology, ADC Therapeutics, Dracen Pharmaceuticals, Janssen, Adela, AstraZeneca, Pionyr, Tempus, VasGene Therapeutics, Gilead, POINT Biopharma, Pfizer, Daiichi Sankyo, Arrowhead Pharmaceuticals, Exelixis, Surface Oncology, and Aravive; has received consulting fees from BMS, Genentech, AVEO and Exelixis, Pfizer, Synthorx, Merck, Corvus, Surface Oncology, Aravive, Alkermes, Arrowhead, Eisai, Nikang Therapeutics, EUSA, Athenex, Debiopharm, and HiberCell; declares previously owned stocks (within the past year) in PTC Therapeutics, a company with approved and pipeline products in muscular dystrophy, metabolic disorders, diffuse intrinsic pontine glioma, and leiomyosarcoma unrelated to the oncology indication discussed here.
Comment on
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Atezolizumab plus cabozantinib versus cabozantinib monotherapy for patients with renal cell carcinoma after progression with previous immune checkpoint inhibitor treatment (CONTACT-03): a multicentre, randomised, open-label, phase 3 trial.Lancet. 2023 Jul 15;402(10397):185-195. doi: 10.1016/S0140-6736(23)00922-4. Epub 2023 Jun 5. Lancet. 2023. PMID: 37290461 Free PMC article. Clinical Trial.
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