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Review
. 2023 Nov;20(9):3898-3905.
doi: 10.1111/iwj.14237. Epub 2023 Jun 9.

Surgical site wound infection and wound pain after video-assisted thoracoscopy in patients with lung cancer: A meta-analysis

Jianhua Zhou  1 , Zhiguo Ren  2 , Xiwen Gao  3 , Xiaohui Zhou  4
Affiliations
Review

Surgical site wound infection and wound pain after video-assisted thoracoscopy in patients with lung cancer: A meta-analysis

Jianhua Zhou et al. Int Wound J. 2023 Nov.

Retraction in

Abstract

A meta-analysis was performed to comprehensively assess the effects of video-assisted thoracoscopy on surgical site wound infection and wound pain in patients with lung cancer. Studies on video-assisted thoracoscopy for lung cancer were collected from PubMed, EMBASE, Cochrane Library, Web of Science, China National Knowledge Infrastructure, Chinese Biomedical Literature Database, and Wanfang database, from inception to January 2023. Two researchers independently screened the literature, extracted the data, and evaluated the quality of the included studies according to the inclusion and exclusion criteria. Meta-analysis was performed using RevMan 5.4 software. Thirty-one articles with a total of 3608 patients were included, with 1809 in the video-assisted thoracoscopy group and 1799 in the control group. Compared with the control group, video-assisted thoracoscopy significantly reduced surgical site wound infection (odds ratio: 0.22, 95% confidence interval [CI]: 0.14-0.33, P < .001) and surgical site wound pain at postoperative day 1 (standardised mean difference [SMD]: -0.90, 95% CI: -1.17 to -0.64, P < .001) and postoperative day 3 (SMD: -1.59, 95% CI: -2.25 to -0.92, P < .001). Thus, these results showed that video-assisted thoracoscopy may have beneficial outcomes by reducing surgical site wound infection and pain. However, owing to the large variation in sample sizes and some methodological shortcomings, further validation is needed in future studies with higher quality and larger sample sizes.

Keywords: wound infection; wound pain.

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Conflict of interest statement

The authors declare that there is no conflict of interest.

Figures

FIGURE 1
FIGURE 1
Study flow diagram.
FIGURE 2
FIGURE 2
The forest plots of surgical site wound infection.
FIGURE 3
FIGURE 3
The forest plots of VAS pain score at 24 h after surgery.
FIGURE 4
FIGURE 4
The forest plots of VAS pain score at 72 h after surgery.
FIGURE 5
FIGURE 5
Funnel plot analysis of wound infection and VAS pain score at 24 h after surgery. (A) wound infection. (B) VAS pain score at 24 h after surgery.
See this image and copyright information in PMC

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