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. 2023 Jun:41 Suppl 1:82-87.
doi: 10.1002/hon.3142.

Peripheral T-cell lymphomas

Alessandro Broccoli  1   2 , Pier Luigi Zinzani  1   2
Affiliations

Peripheral T-cell lymphomas

Alessandro Broccoli et al. Hematol Oncol. 2023 Jun.

Abstract

The treatment of peripheral T-cell lymphomas is challenging, as they often display a severe prognosis and lack effective treatment strategies. We will try to answer three burning questions: can we differentiate the initial treatment based on the histotype and the clinical presentation of peripheral T-cell lymphoma patients? Do we require an autologous stem cell transplantation in all patients? Is there room for improvement in the setting of relapsed and refractory disease?

Keywords: azacitidine; brentuximab vedotin; duvelisib; golidocitinib; linperlisib; peripheral T-cell lymphomas; valemetostat.

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References

REFERENCES

    1. Campo E, Jaffe ES, Cook JR, et al. The international consensus classification of mature lymphoid neoplasms: a report from the clinical advisory committee. Blood. 2022;140(11):1229-1253. https://doi.org/10.1182/blood.2022015851
    1. Alaggio R, Amador C, Anagnostopoulos I, et al. The 5th edition of the World Health Organization classification of hematolymphoid tumours: lymphoid neoplasms. Leukemia. 2022;36(7):1720-1748. https://doi.org/10.1038/s41375-022-01620-2
    1. Abouyabis AN, Shenoy PJ, Sinha R, Flowers CR, Lechowicz MJ. A systematic review and meta-analysis of front-line anthracycline-based chemotherapy regimens for peripheral T-cell lymphoma. ISRN Hematol. 2011;2011:623924-624014. https://doi.org/10.5402/2011/623924
    1. Abramson JS, Feldman T, Kroll-Desrosiers AR, et al. Peripheral T-cell lymphomas in a large US multicentre cohort: prognostication in the modern era including impact of frontline therapy. Ann Oncol. 2014;25(11):2211-2217. https://doi.org/10.1093/annonc/mdu443
    1. Briski R, Feldman AL, Bailey NG, et al. The role of front-line anthracycline-containing chemotherapy regimens in peripheral T-cell lymphomas. Blood Cancer J. 2014;4(5):e214. https://doi.org/10.1038/bcj.2014.34

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