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Review
. 2023 May 30;15(11):2981.
doi: 10.3390/cancers15112981.

Natural Products for the Prevention, Treatment and Progression of Breast Cancer

Fabiano Svolacchia  1   2 , Sergio Brongo  3 , Alessia Catalano  4 , Agostino Ceccarini  5 , Lorenzo Svolacchia  1 , Alessandro Santarsiere  6   7 , Carmen Scieuzo  6   8 , Rosanna Salvia  6   8 , Francesca Finelli  9 , Luigi Milella  6 , Carmela Saturnino  6 , Maria Stefania Sinicropi  10 , Tommaso Fabrizio  11 , Federica Giuzio  5   6   12
Affiliations
Review

Natural Products for the Prevention, Treatment and Progression of Breast Cancer

Fabiano Svolacchia et al. Cancers (Basel). .

Abstract

In this review, we summarize the most used natural products as useful adjuvants in BC by clarifying how these products may play a critical role in the prevention, treatment and progression of this disease. BC is the leading cancer, in terms of incidence, that affects women. The epidemiology and pathophysiology of BC were widely reported. Inflammation and cancer are known to influence each other in several tumors. In the case of BC, the inflammatory component precedes the development of the neoplasm through a slowly increasing and prolonged inflammation that also favors its growth. BC therapy involves a multidisciplinary approach comprising surgery, radiotherapy and chemotherapy. There are numerous observations that showed that the effects of some natural substances, which, in integration with the classic protocols, can be used not only for prevention or integration in order to prevent recurrences and induce a state of chemoquiescence but also as chemo- and radiosensitizers during classic therapy.

Keywords: breast cancer; chemoscience; natural anticancer agents; prolonged inflammation.

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Conflict of interest statement

The authors declare no conflict of interest.

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